Results 151 to 160 of about 24,372,729 (260)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

01517 MOVE Service Trip

MOVE volunteers posing in the kitchen while working during a service ...

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Go West? Assessing the willingness to move from Central and Eastern European Countries [PDF]

This paper uses cross national survey data to examine the willingness to move of residents from several Central and Eastern European Countries (CEECs).
Stephen Drinkwater
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A Qualitative Descriptive Study of Motivation States for Physical Activity Among Middle-Aged Adults With Type 1 Diabetes Mellitus. [PDF]

J Phys Act Health
Wang X, Ash GI, Hernandez E, Stults-Kolehmainen M, Griggs SA.   +4 more
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

01503 MOVE Service Trip

New roof for an old house being worked on during a MOVE service ...

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A Longitudinal Analysis of Moving Desires, Expectations and Actual Moving Behaviour [PDF]

Many theories of residential mobility contend that individuals express a sequence of moving desires, intentions and expectations prior to moving. Much research has investigated how individuals form these pre-move thoughts, with a largely separate ...
Feijten, Peteke, van Ham, Maarten, Coulter, Rory   +2 more
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Palovarotene impact on fibrodysplasia ossificans progressiva (FOP): data from month 48 of the phase III MOVE trial. [PDF]

JBMR Plus
Pignolo RJ, Hsiao EC, Al Mukaddam M, Baujat G, Berglund SK, Cheung AM, De Cunto C, Delai P, Haga N, Kannu P, Mancilla EE, Marino R, Shih F, Strahs A, Kaplan FS.   +14 more
europepmc   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Time to move: arthritis

, 2014
The strategy outlined in this document provides a road map for improving care across Australia for people with arthritis and aims to reduce the costs to society of arthritis related diseases.

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