Results 61 to 70 of about 465,667 (260)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Move, Dither, Move, Dither. On the Structure of Random Walks and Single-Particle Trajectories [PDF]
Biophysical Journal, 2011 The fundamental principle in interpreting single-particle trajectories is that a pure random walk is the control and null hypothesis. In order to make any claim about a putative physical or biological event in an observed single-particle trajectory, one must evaluate the probability that the event could have occurred by chance in the corresponding pure
openaire +2 more sources
Verb-Governor Based Comparative Analysis on the Move Structure of Abstracts in Six English Varieties
This study compares the move structure of abstracts in six English varieties based on verb-governors to explore their similarities and differences. In this study, we use English abstracts in journals published in six official languages of the United ...
Chen, Shuo, Cao, Jingxiang
core +1 more source
Contests – A comparison of timing and information structures [PDF]
, 2011 We study a model of imperfectly discriminating contests with two ex ante symmetric agents. We consider four institutional settings: Contestants move either sequentially or simultaneously and in addition their types are either public or private ...
Sandra Ludwig, Ludwig, Sandra
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
New local move operators for Bayesian networks structure learning
, 2012 We propose new local move operators incorporated into a score-based stochastic greedy search algorithm to e ciently escape from local optima in the search space of directed acyclic graphs.
Mangin, Brigitte +2 more
core
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
01276 MOVE Volunteers posing in front of a structure they are helping build
MOVE students in front of a structure they are helping ...
core
, 2018 Post hoc Tukey test results of the frequency of initial step(s) in the move structure across various science disciplines.
Rita Gill Singh (5851520) +2 more
core +1 more source