Results 51 to 60 of about 1,529,473 (248)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

The signifier in motion: the movement of language in Psychoanalysis and in Aristotle’s linguistic theory

Fractal: Revista de Psicologia
The article examines the relation between language and movement in Freud’s Project for a Scientific Psychology and Lacan’s seminars four and seven, in the first of which Lacan aligns the anguishing movement in which the subject knows he is caught up with
Shirley Sharon-Zisser
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Aggregation Behaviour as an Adaptive Reproductive Strategy in a Marine Ecosystem Engineer

Ecology and Evolution
Aggregation behaviour is a key process shared by numerous organisms, providing benefits such as predator protection, resistance to abiotic stressors and enhancing reproductive success.
Marine Uguen, Sylvie M. Gaudron, Alexandre Rahoui‐Davoust, Valérie Lefebvre, Laurent Seuront   +4 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

The Impact of Abdominal Drawing-in Maneuver and Tensor Fasciae Lataeiliotibial Band Self-stretching on Lumbopelvic Kinematics in Individuals With Lumbar Extension Rotation Syndrome

Physical Therapy Korea
Background: The abdominal drawing-in maneuver (ADIM), a method of lumbar stabilization training, is an effective neuromuscular intervention for lumbar instability associated with low back pain (LBP).
One-bin Lim, Oh-yun Kwon, Heon-seock Cynn, Chung-hwi Yi   +3 more
doaj   +1 more source

Western spotted skunk spatial ecology in the temperate rainforests of the Pacific Northwest

Ecosphere
A major threat to small mammalian carnivore populations is human‐induced land use change, but conservation and management are inhibited by limited knowledge about their ecology and natural history. To fill a key knowledge gap of the western spotted skunk
Marie I. Tosa, Damon B. Lesmeister, Taal Levi   +2 more
doaj   +1 more source

Quantifying Arm and Leg Movements in 3-Month-Old Infants Using Pose Estimation: Proof of Concept

Sensors
Background: Pose estimation (PE) has the promise to measure pediatric movement from a video recording. The purpose of this study was to quantify the accuracy of a PE model to detect arm and leg movements in 3-month-old infants with and without (TD, for ...
Marcelo R. Rosales, Janet Simsic, Tondi Kneeland, Jill Heathcock   +3 more
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source