Results 71 to 80 of about 1,562,108 (268)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Humpback Whale Movements and Behavior in Response to Whale-Watching Vessels in Juneau, AK

open access: yesFrontiers in Marine Science, 2019
The whale-watching industry in Juneau, Alaska relies primarily on the presence of North Pacific humpback whales (Megaptera novaeangliae). To meet demands from the rapidly growing tourism industry, the number of whale-watching vessels in this region has ...
Alicia R. Schuler   +7 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Upper Limb Kinematics in Stroke and Healthy Controls Using Target-to-Target Task in Virtual Reality

open access: yesFrontiers in Neurology, 2018
BackgroundKinematic analysis using virtual reality (VR) environment provides quantitative assessment of upper limb movements. This technique has rarely been used in evaluating motor function in stroke despite its availability in stroke rehabilitation ...
Netha Hussain   +2 more
doaj   +1 more source

Movement Assessment Battery for Children (Movement ABC)

open access: yesAustralian Journal of Physiotherapy, 2006
The Movement ABC (Henderson and Sugden 1992) is the most commonly reported norm-ranked assessment used to determine the presence of Developmental Co-ordination Disorder (DCD) in school-aged children. The assessment provides quantitative and qualitative data about a child’s performance of age-appropriate tasks within 3 subsections: Manual Dexterity ...
Watter, Pauline, Johnston, Leanne
openaire   +4 more sources

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Post-Movement Beta Synchrony Inhibits Cortical Excitability

open access: yesBrain Sciences
Background/Objectives: This study investigates the relationship between movement-related beta synchrony and primary motor cortex (M1) excitability, focusing on the time-dependent inhibition of movement. Voluntary movement induces beta frequency (13–30 Hz)
Edward Rhodes   +3 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

The benefit of hippotherapy for improvement of attention and memory in children with cerebral palsy: A pilot study

open access: yesActa Gymnica, 2015
Background: The research is based on an assumption that the hypokinesia induced by cerebral palsy (CP) leads to inhibition of some mental functions. The method we used to treat patients with CP, hippotherapy (HT), is a treatment using horses and belongs ...
Eva Krejčí   +2 more
doaj   +1 more source

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