Results 81 to 90 of about 1,791,136 (249)
Механика машин, механизмов и материалов, 2011 It is shown that motion generates new information in a system if its damage index is nonzero; information turns out to be positive when the system is strengthened and negative when it softens.
L.A. Sosnovskiy
doaj
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Diurnal and nocturnal movements of Kori Bustards in the Serengeti ecosystem
Journal of Field Ornithology, 2022 Although Kori Bustards (Ardeotis kori) are reported as diurnal, the species’ activity patterns have not been assessed to date. We report on the movement during different parts of the day of eight GPS-tagged individuals in the Serengeti ecosystem ...
Emmanuel C. Mmassy +5 more
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Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Aerobic Brain Metabolism, Body Temperature, Oxygen, Fetal Oxygen Supply and Fetal Movement Dynamics as Factors in Stillbirth and Neonatal Encephalopathy: Invention Review [PDF]
, 2023 Natalya Urakova +3 more
openalex +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
ABDURREZZÂK EL-LÂHÎCÎ’DE SUDÛRUN İMKÂNI BAĞLAMINDA SOYUT CEVHERLER
Fırat Üniversitesi İlahiyat Fakültesi Dergisi, 2016 Felsefe ve kelam arasında cereyan eden önemli tartışmalardan biri de hiç şüphesiz “sudûr teorisi”dir. Filozoflar söz konusu bu teorinin imkân ve tutarlılığını mücerred cevherler/akıl ve nefs” kavramı üzerinden izah etmeye çalışmışlardır.
Ahmet Pirinç
doaj
Football boot insoles and sensitivity to extent of ankle inversion movement [PDF]
, 2003 Gordon Waddington, Roger Adams
openalex +1 more source