Results 61 to 70 of about 4,282,757 (297)
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Nauka ta progres transportu, 2015 Purpose. The value of drive resistance to its movement is the main parameter at calculating the drive power of bridge crane. The value of the wheel rolling friction on the rails is one of the important parts of the resistance to movement. It is necessary
V. M. Bohomaz +3 more
doaj +1 more source
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
FEBS Letters, EarlyView.In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
MATEC Web of Conferences, 2018 The directions associated with development and improvement in the field of works' production using the concrete and reinforced concrete are related mainly with the improvement of the quality and durability of concrete and products based on it, the ...
Novikov Sergey +2 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Reduction of Kinematic Resistance To Movement Of the Railway Vehicles
MATEC Web of Conferences, 2018 The aim of the work is to reduce the train rolling resistance to movement the railway vehicles. The article proves the expediency of changing the constructive scheme of railway vehicle wheel, which allows independent rotation their wheel mounting surface
Mikhailov E. +3 more
doaj +1 more source
Salicylic Acid Can Induce Resistance to Plant Virus Movement
Molecular Plant-Microbe Interactions, 1998 Salicylic acid (SA) treatment has recently been reported to inhibit replication of tobacco mosaic virus (TMV) in inoculated tissue. Furthermore, resistance is induced via a novel defensive signal transduction pathway sensitive to inhibition by ...
Martin Naylor +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
, 2003 The Bulletin was the official newsletter of the New Unity Movement. It was published about twice a year and contained articles reflecting the organisation's views on resistance to the Apartheid ...
core +2 more sources