Results 71 to 80 of about 1,543,813 (309)

Transgenic resistance to PMTV and PVA provides novel insights to viral long-distance movement [PDF]

open access: yes, 2005
The studies in this thesis describe forms of transgenic resistance to plant viruses and how they can be used for studying viral infection cycle. S. tuberosum cv.
Germundsson, Anna
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Globalising resistance: social movement activism in Malawi [PDF]

open access: yes, 2011
Attendant with the rise of the good governance discourse of the 1990s and beyond, contemporary research on social activism in Africa has tended to be rooted in normalised conceptions of civil society operating in partnership with the state.
Gaynor, Niamh
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

METHOD OF THE DRIVE POWER DETERMINATION OF THE MECHANISMS OF THE BRIDGE CRANE MOVEMENT CONSIDERING THE ROLLING FRICTION

open access: yesNauka ta progres transportu, 2015
Purpose. The value of drive resistance to its movement is the main parameter at calculating the drive power of bridge crane. The value of the wheel rolling friction on the rails is one of the important parts of the resistance to movement. It is necessary
V. M. Bohomaz   +3 more
doaj   +1 more source

#MeToo as Catalyst: A Glimpse into 21st Century Activism [PDF]

open access: yes, 2019
The Twitter hashtag #MeToo has provided an accessible medium for users to share their personal experiences and make public the prevalence of sexual harassment, assault, and violence against women.
Mezey, Naomi   +2 more
core   +2 more sources

The internationalisation of nonviolent resistance: the case of the BDS campaign [PDF]

open access: yes, 2018
This paper seeks to identify some of the factors that can enhance the strength and influence of international civil society solidarity networks that mobilise around issues of concern.
Darweish, Marwan, Rigby, Andrew
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Loci Controlling Resistance to High Plains Virus and Wheat Streak Mosaic Virus in a B73 × Mo17 Population of Maize [PDF]

open access: yes, 1999
High Plains disease has the potential to cause significant yield loss in susceptible corn (Zea mays L.) and wheat (Triticum aestivum L.) genotypes, especially in the central and western USA.
Jensen, S. G.   +4 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

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