Results 71 to 80 of about 1,535,246 (311)

Effects of Laryngeal Restriction on Pharyngeal Peristalsis and Biomechanics: Clinical Implications [PDF]

open access: yes, 2016
To date, rehabilitative exercises aimed at strengthening the pharyngeal muscles have not been developed due to the inability to successfully overload and fatigue these muscles during their contraction, a necessary requirement for strength training.
Balasubramanian, Gokulakrishnan   +5 more
core   +2 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Critical Facets of European Corn Borer Adult Movement Ecology Relevant to Mitigating Field Resistance to Bt-Corn

open access: yesInsects
The European corn borer (Ostrinia nubilalis, Hübner) has been managed successfully in North America since 1996 with transgenic Bt-corn. However, field-evolved resistance to all four available insecticidal Bt proteins has been detected in four provinces ...
Thomas W. Sappington
doaj   +1 more source

\u3cem\u3eArabidopsis\u3c/em\u3e AZI1 Family Proteins Mediate Signal Mobilization for Systemic Defence Priming [PDF]

open access: yes, 2015
Priming is a major mechanism behind the immunological \u27memory\u27 observed during two key plant systemic defences: systemic acquired resistance (SAR) and induced systemic resistance (ISR).
Cecchini, Nicolas M.   +4 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

METHOD OF THE DRIVE POWER DETERMINATION OF THE MECHANISMS OF THE BRIDGE CRANE MOVEMENT CONSIDERING THE ROLLING FRICTION

open access: yesNauka ta progres transportu, 2015
Purpose. The value of drive resistance to its movement is the main parameter at calculating the drive power of bridge crane. The value of the wheel rolling friction on the rails is one of the important parts of the resistance to movement. It is necessary
V. M. Bohomaz   +3 more
doaj   +1 more source

Analysis of the potential mechanisms of rockbursts [PDF]

open access: yes, 2006
Sudden slip on geological faults or other discontinuities in rock may be preceded by an initial phase of "slow" fault creep. A simple plane strain model of a suddenly loaded fault is analysed to illustrate the possible transition from stable slip ...
Napier, J.A.L.
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Theoretical basics and experimental methods of consideration of the concrete mixtures' movement resistance in the concrete-delivery pipelines

open access: yesMATEC Web of Conferences, 2018
The directions associated with development and improvement in the field of works' production using the concrete and reinforced concrete are related mainly with the improvement of the quality and durability of concrete and products based on it, the ...
Novikov Sergey   +2 more
doaj   +1 more source

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