Results 41 to 50 of about 891,007 (292)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

L’expérience du quotidien dans Buffy the Vampire Slayer

open access: yesMise au Point, 2021
Everyday life is a notion often considered to be vague. Nevertheless social sciences and humanities conceptualize it in a way which enables it to grasp its different levels and from which the relationship to everyday life in audiovisual fiction can be ...
Hélène Monnet-Cantagrel
doaj   +1 more source

Theme and Rheme of Main Character Script in Hachiko Movie [PDF]

open access: yes, 2013
This Study Deals with the Theme and Rheme of Main Character Script in Hachiko Movie. The Objective of the study are to find out the kinds of thematic progression that is used in Hachiko movie, to find out the kinds of Theme that is used in Hachiko movie,
Pasaribu, T. M. (Tohom)   +1 more
core  

Imaging Orbital-selective Quasiparticles in the Hund's Metal State of FeSe [PDF]

open access: yes, 2018
Strong electronic correlations, emerging from the parent Mott insulator phase, are key to copper-based high temperature superconductivity (HTS). By contrast, the parent phase of iron-based HTS is never a correlated insulator.
Andersen, B. M.   +9 more
core   +5 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

La communication multimodale à l’appui de la traduction [PDF]

open access: yesAnadiss, 2022
Thanks to the translation of comics into cartoons and movies, the audience fascinated by heroes and superheroes has grown exponentially. Multimodal communication has boosted reading, and consequently the translation of comics that are considered as ...
MANOLACHE, Simona-Aida
doaj  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Getting Lost ‘Into the Wild’: Understanding Consumers’ Movie Enjoyment Through a Narrative Transportation Approach [PDF]

open access: yes, 2008
As consumers enjoy watching movies for many reasons, this paper takes an existential-phenomenological perspective to discuss movie consumption as holistic private lived experiences.
Batat, Wided, Wohlfeil, Markus
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Anthropological Analysis of the Depiction of Deprivation in Old Age In the Case of the Movie Night Boats

open access: yesEtnoantropološki Problemi
This anthropological analysis focuses on the Croatian feature film Night Boats (2012), directed by Igor Mirković. The subject of the movie is a partnership that develops between two residents of a nursing home in Zagreb, highlighting, among other things,
Ljubica Milosavljević, Mladen Stajić
doaj   +1 more source

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