Results 41 to 50 of about 248,724 (255)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

L’expérience du quotidien dans Buffy the Vampire Slayer

open access: yesMise au Point, 2021
Everyday life is a notion often considered to be vague. Nevertheless social sciences and humanities conceptualize it in a way which enables it to grasp its different levels and from which the relationship to everyday life in audiovisual fiction can be ...
Hélène Monnet-Cantagrel
doaj   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Prediction techniques of movie box office using neural networks and emotional mining

open access: yesScientific Reports
Box office prediction is of great significance for understanding investment risks, class construction, promotion and distribution, and theater scheduling.
Zhuqing Zhang, Yutong Meng, Daibai Xiao
doaj   +1 more source

Anthropological Analysis of the Depiction of Deprivation in Old Age In the Case of the Movie Night Boats

open access: yesEtnoantropološki Problemi
This anthropological analysis focuses on the Croatian feature film Night Boats (2012), directed by Igor Mirković. The subject of the movie is a partnership that develops between two residents of a nursing home in Zagreb, highlighting, among other things,
Ljubica Milosavljević, Mladen Stajić
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

An Exploring Obstacles and Teaching Strategies Used by Main Character in “Like Stars on Earth” Movie

open access: yesSALEE
Speech act study is important for our daily because it gives a comprehension of what message is discovered in every utterance. Austin (1962) stated that in uttering a sentence, a speaker is generally involved in three levels of speech acts, they are ...
Mufida Nadira Yuni Pureka   +1 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Analysis of Deixis in the Subtitle Movie of “First Kiss”

open access: yesLET: Linguistics, Literature and English Teaching Journal, 2020
The objective of this research is to analyze the type and its examples of deixis found in the subtitle movie of “First Kiss”. This research method of this method is qualitative methodology.
Tira Nur Fitria
doaj   +1 more source

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