Results 61 to 70 of about 171,053 (214)
Estimation of LD50 by moving averages [PDF]
Journal of Hygiene, 1952 Methods of graduation of a series of observations by means of moving averages were discussed by Sheppard (1914), and subsequently by Sherriff (1920) and a number of other writers. These methods based on least squares or weighted least squares solutions differ from actuarial or summation methods.
openaire +3 more sources
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
HDAC4 regulates apoptosis in Acan‐CreERT2;HDAC4d/d mice with osteoarthritis by downregulating ATF4
FEBS Open Bio, EarlyView.Using the AcanCreERT2;HDAC4fl/fl genetic mouse model, we further investigated the role of histone deacetylase 4 (HDAC4) in chondrocyte apoptosis. We found that knocking down HDAC4 may be associated with chondrocyte apoptosis by upregulating the activating transcription factor 4 (ATF4)/CAAT/enhancer binding protein homologous (CHOP) signaling pathway ...
Jingrui Huang +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.FAM136A depletion upregulated ROS production, reduced mitochondrial membrane potential (ΔΨ) and ATP production, and upregulated expression of PCK1, PCK2, HMGCS1, and HMGCS2. The expression of both TOMM22 and TOMM20 was also upregulated. FAM136A depletion reduced HCCS that produce holocytochrome c by combining heme to apocytochrome c, and reduced the ...
Yushi Otsuka, Masato Yano
wiley +1 more source
High-frequency sampling of multivariate CARMA processes [PDF]
arXiv, 2015 High-frequency sampled multivariate continuous time autoregressive moving average processes are investigated. We obtain asymptotic expansion for the spectral density of the sampled MCARMA process $(Y_{n\Delta})_{n \in \mathbb{Z}}$ as $\Delta \downarrow 0$, where $(Y_t)_{t \in \mathbb{R}}$ is an MCARMA process. We show that the properly filtered process
arxiv
On Moving Average Parameter Estimation [PDF]
, 2012 Publication in the conference proceedings of EUSIPCO, Bucharest, Romania ...
Prabhu Babu +2 more
openaire +3 more sources
A potential tumor suppressor role of PLK2 in glioblastoma
FEBS Open Bio, EarlyView.PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia +5 more
wiley +1 more source
A Synchronization Algorithm Based on Moving Average for Robust Audio Watermarking Scheme [PDF]
arXiv, 2017 A synchronization code scheme based on moving average is proposed for robust audio watermarking in the paper. Two proper positive integers are chosen to compute the moving average sequence by sliding one sample every time. The synchronization bits are embedded at crosses of the two moving average sequences with the quantization index modulation.
arxiv
Red blood cells could protect miRNAs from degradation or loss thanks to Argonaute 2 binding
FEBS Open Bio, EarlyView.The present work investigates the presence and the stability of miRNAs into RBCs, both native and engineered. The observed stability is due to the Ago2 bound resulting in minimal RISC. Indeed, if the miRNA‐Ago2 complex is present, miRNAs are protected from release or degradation and they are biologically active. Thus, RBCs can act as miRNA carriers for
Elena Perla +4 more
wiley +1 more source
Berry-Esséen Bounds for Long Memory Moving Averages via Stein's Method and Malliavin Calculus [PDF]
Stoch. Anal. Appl. 29 (2011), no. 5, 881-905, 2010 Using the Stein method on Wiener chaos introduced by Nourdin and Peccati we prove Berry-Ess\'een bounds for long memory moving averages.
arxiv