Results 101 to 110 of about 475,199 (278)
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Examination of the Armagh Observatory Annual Mean Temperature Record, 1844-2004 [PDF]
The long-term annual mean temperature record (1844-2004) of the Armagh Observatory (Armagh, Northern Ireland, United Kingdom) is examined for evidence of systematic variation, in particular, as related to solar/geomagnetic forcing and secular variation ...
Hathaway, David H., Wilson, Robert M.
core +1 more source
Vector Autoregressive Moving Average Model with Scalar Moving Average
, 2019 We show Vector Autoregressive Moving Average models with scalar Moving Average components could be estimated by generalized least square (GLS) for each fixed moving average polynomial. The conditional variance of the GLS model is the concentrated covariant matrix of the moving average process.
openaire +2 more sources
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
A Dynamic Analysis of Moving Average Rules [PDF]
The use of various moving average rules remains popular with financial market practitioners. These rules have recently become the focus of empirical studies.
Carl Chiarella +2 more
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Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
Testing the Profitability of Simple Technical Trading Rules: A Bootstrap Analysis of the Italian Stock Market. [PDF]
The aim of this paper consists in testing the profitability of simple technical trading rules in the Italian stock market. By means of a recently developed bootstrap methodology we assess whether technical rules based on moving averages are capable of ...
Amedeo Gazzini, Marco Bee
core
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
A Long-Term Analysis of Changes in Farm Size and Financial Performance [PDF]
This paper examined the changing structure of farms in Kansas. Specifically, changes in farm size, farm type, financial performance, and economies of size were examined using five-year moving averages from 1973 to 2007.
Langemeier, Michael R., Snider, Lindsey
core +1 more source