Results 81 to 90 of about 1,101,560 (296)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
npj Materials DegradationIncongruent corrosion of silicate glass is modeled as a moving-boundary transport problem, where the moving boundary contributes convective transport and the ion exchange provides diffusive transport.
Andrew L. Ogrinc +2 more
doaj +1 more source
Well-posedness for the classical Stefan problem and the zero surface tension limit [PDF]
, 2016 We develop a framework for a unified treatment of well-posedness for the Stefan problem with or without surface tension. In the absence of surface tension, we establish well-posedness in Sobolev spaces for the classical Stefan problem. We introduce a new
Hadzic, Mahir, Shkoller, Steve
core
On Schr\"odinger's equation, 3-dimensional Bessel bridges, and passage time problems
, 2010 In this work we relate the density of the first-passage time of a Wiener process to a moving boundary with the three dimensional Bessel bridge process and a solution of the heat equation with a moving boundary.
Hernandez-del-Valle, Gerardo
core +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
AxiomsIn this paper, we propose an efficient numerical method to solve the problems of diffusive logistic models with free boundaries, which are often used to simulate the spreading of new or invasive species.
Chunyan Zhang, Yuanyang Qiao
doaj +1 more source
On the use of local max-ent shape functions for the simulation of forming processes [PDF]
, 2009 In this work we review the opportunities given by the use of local maximum-\ud entropy approximants (LME) for the simulation of forming processes.
Boogaard, A.H. van den +3 more
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
A spatial epidemic model with a moving boundary. [PDF]
Infect Dis Model, 2021 Zhuang Q, Wang J.
europepmc +1 more source
Invasion moving boundary problem for a biofilm reactor model
, 2017 The work presents the analysis of the free boundary value problem related to the invasion model of new species in biofilm reactors. In the framework of continuum approach to mathematical modelling of biofilm growth, the problem consists of a system of ...
D'Acunto, Berardino +3 more
core +1 more source