Results 41 to 50 of about 547,462 (296)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Comparison of meshfree displacement and stress error recovery of finite element solutions using moving least squares interpolation

Advances in Mechanical Engineering, 2022
The moving least square (MLS) interpolation based the recovery procedures have been successfully applied to recover the finite element solution errors in the analysis of elastic plates and pipes problems and can be advantageously applied for large ...
Mohd. Ahmed, Devinder Singh, Saeed AlQadhi, Majed A Alrefae   +3 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

A Geometry Constrained Moving Least Squares-based High-precision 3D Reconstruction Method of Mountains from TomoSAR Point Clouds

Leida xuebao, 2022
Tomographic Synthetic Aperture Radar (TomoSAR) is an advanced technology for three-dimensional (3D) mountain reconstruction. However, the TomoSAR mountain point clouds have a significant location error in the elevation direction, making high-precision 3D
Xiaowan LI, Xingdong LIANG, Fubo ZHANG, Yunlong LIU, Yanlei LI, Qichang GUO, Yangliang WAN, Xiangxi BU   +7 more
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

3D Reconstruction Based on Iterative Optimization of Moving Least-Squares Function

Algorithms
Three-dimensional reconstruction from point clouds is an important research topic in computer vision and computer graphics. However, the discrete nature, sparsity, and noise of the original point cloud contribute to the results of 3D surface generation ...
Saiya Li, Jinhe Su, Guoqing Jiang, Ziyu Huang, Xiaorong Zhang   +4 more
doaj   +1 more source

A Modification of the Moving Least-Squares Approximation in the Element-Free Galerkin Method

Journal of Applied Mathematics, 2014
The element-free Galerkin (EFG) method is one of the widely used meshfree methods for solving partial differential equations. In the EFG method, shape functions are derived from a moving least-squares (MLS) approximation, which involves the inversion of ...
Yang Cao, Jun-Liang Dong, Lin-Quan Yao
doaj   +1 more source

AO–MW–PLS method applied to rapid quantification of teicoplanin with near-infrared spectroscopy [PDF]

Journal of Innovative Optical Health Sciences, 2017
Teicoplanin (TCP) is an important lipoglycopeptide antibiotic produced by fermenting Actinoplanes teichomyceticus. The change in TCP concentration is important to measure in the fermentation process. In this study, a reagent-free and rapid quantification
Jiemei Chen, Tian Ai, Tao Pan, Lijun Yao, Fenggeng Xia   +4 more
doaj   +1 more source

Methods for Fitting the Limit State Function of the Residual Strength of Damaged Ships

Journal of Marine Science and Engineering, 2022
The limit state function is important for the assessment of the longitudinal strength of damaged ships under combined bending moments in severe waves.
Zhiyao Zhu, Huilong Ren, Xiuhuan Wang, Nan Zhao, Chenfeng Li   +4 more
doaj   +1 more source