Results 61 to 70 of about 547,462 (296)

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Moving-Least-Squares-Enhanced 3D Object Detection for 4D Millimeter-Wave Radar

Remote Sensing
Object detection is a critical task in autonomous driving. Currently, 3D object detection methods for autonomous driving primarily rely on stereo cameras and LiDAR, which are susceptible to adverse weather conditions and low lighting, resulting in ...
Weigang Shi, Panpan Tong, Xin Bi
doaj   +1 more source

On the use of local max-ent shape functions for the simulation of forming processes [PDF]

, 2009
In this work we review the opportunities given by the use of local maximum-\ud entropy approximants (LME) for the simulation of forming processes.
Boogaard, A.H. van den, Cueto, E., Gonzalez, D., Quak, W.   +3 more
core   +1 more source

A least-squares implicit RBF-FD closest point method and applications to PDEs on moving surfaces

, 2019
The closest point method (Ruuth and Merriman, J. Comput. Phys. 227(3):1943-1961, [2008]) is an embedding method developed to solve a variety of partial differential equations (PDEs) on smooth surfaces, using a closest point representation of the surface ...
Ling, L., Petras, A., Piret, C., Ruuth, S. J.   +3 more
core   +1 more source

Adult‐Onset Subacute Sclerosing Panencephalitis Presenting With Subacute Cognitive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We describe the case of a 41‐year‐old man diagnosed with adult‐onset subacute sclerosing panencephalitis (SSPE). The patient presented with subacute progressive cognitive deficits and a neuropsychological profile indicating predominant frontoparietal dysfunction. MRI showed only mild parietal‐predominant cerebral atrophy.
Dennis Yeow, Nicola McKern, Vincent Oxenham, Kate Ahmad, Omar Ahmad   +4 more
wiley   +1 more source

Solving weakly singular integral equations utilizing the meshless local discrete collocation technique

Alexandria Engineering Journal, 2018
The current work presents a computational scheme to solve weakly singular integral equations of the second kind. The discrete collocation method in addition to the moving least squares (MLS) technique established on scattered points is utilized to ...
Pouria Assari
doaj   +1 more source

AUTOMATIC EXTRACTION OF ROCK JOINTS FROM LASER SCANNED DATA BY MOVING LEAST SQUARES METHOD AND FUZZY K-MEANS CLUSTERING [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2012
Recent development of laser scanning device increased the capability of representing rock outcrop in a very high resolution. Accurate 3D point cloud model with rock joint information can help geologist to estimate stability of rock slope on-site or off ...
S. Oh, H. D. Park, Y. D. Jo
doaj   +1 more source

Enhancing SPH using moving least-squares and radial basis functions [PDF]

, 2005
In this paper we consider two sources of enhancement for the meshfree Lagrangian particle method smoothed particle hydrodynamics (SPH) by improving the accuracy of the particle approximation.
Brownlee, R., Houston, Paul, Levesley, J., Rosswog, S.   +3 more
core  

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source