Results 51 to 60 of about 4,063,184 (303)

A Hybrid Interpolating Meshless Method for 3D Advection–Diffusion Problems

Mathematics, 2022
A hybrid interpolating meshless (HIM) method is established for dealing with three-dimensional (3D) advection–diffusion equations. To improve computational efficiency, a 3D equation is changed into correlative two-dimensional (2D) equations. The improved
Zhijuan Meng, Xiaofei Chi, Lidong Ma
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Element-Free Galerkin Scaled Boundary Method Based on Moving Kriging Interpolation for Steady Heat Conduction Analysis with Temperatures on Side-Faces

Shanghai Jiaotong Daxue xuebao, 2021
The element-free Galerkin scaled boundary method (EFG-SBM) based on moving Kriging (MK) interpolation is used to solve steady heat conduction problems with temperature loads on side-faces, in which the circumferential boundary is discretized based on MK ...
WANG Feng, CHEN Jiali, CHEN Denghong, FAN Yong, LI Zhiyuan, HE Weiping
doaj   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Analysis of Meshfree Galerkin Methods Based on Moving Least Squares and Local Maximum-Entropy Approximation Schemes

Mathematics
Over the last two decades, meshfree Galerkin methods have become increasingly popular in solid and fluid mechanics applications. A variety of these methods have been developed, each incorporating unique meshfree approximation schemes to enhance their ...
Hongtao Yang, Hao Wang, Bo Li
doaj   +1 more source

Analysis of Beams with Transversal Gradations of the Young's Modulus and Variable Depths by the Meshless Method

Slovak Journal of Civil Engineering, 2014
A numerical analysis based on the meshless local Petrov- Galerkin (MLPG) method is proposed for a functionally graded material FGM (FGMfunctionally graded material) beam.
Sátor Ladislav, Sládek Vladimír, Sládek Ján   +2 more
doaj   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Meshless Local Petrov–Galerkin Formulation of Inverse Stefan Problem via Moving Least Squares Approximation

, 2019
In this paper, we study the meshless local Petrov–Galerkin (MLPG) method based on the moving least squares (MLS) approximation for finding a numerical solution to the Stefan free boundary problem. Approximation of this problem, due to the moving boundary,
A. Karami, S. Abbasbandy, E. Shivanian
semanticscholar   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Overview of total least squares methods

, 2007
We review the development and extensions of the classical total least squares method and describe algorithms for its generalization to weighted and structured approximation problems.
Markovsky, Ivan, Van Huffel, Sabine
core   +1 more source