Results 31 to 40 of about 2,227,949 (244)
Parameters Identification of Moving Load Using ANN and Dynamic Strain
Shock and Vibration, 2016 Moving load identification is an important part of bridge structure health monitoring; accurate and reliable load data can be used to check the load of bridge design, and the load spectrum can provide a more practical basis for structural fatigue ...
Hui Yang, Weiming Yan, Haoxiang He
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
MOVING in the Swiss Alps [PDF]
Agriculture has a long tradition in the Grison Alps and plays a major role in forming the typical landscape. Within MOVING, we elaborated the mountain grain value chain and its importance to diversify the region’s traditional animal agriculture with ...
Jaisli, Isabel, Forrer, Carmen
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Application of the Random Decrement Technique in Damage Detection under Moving Load
Applied Sciences, 2018 This paper employs the random decrement technique as an output-only method to detect damage from the acceleration signals under a moving load. The random decrement technique is an especial averaging method that produces Random Decrement Signatures (RDS).
Hadi Kordestani +3 more
doaj +1 more source
Dynamic Load Test and Contact Force Analysis of the AERORail Structure
Applied Sciences, 2023 The flexible structure of the new type of aerial track studied in this paper is formed by strings and tracks, which have obvious dynamic characteristics under the action of vehicle moving loads and is also an important factor affecting its performance ...
Fangyuan Li +3 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source