Results 101 to 110 of about 125,636 (269)
O pewnym quasi-ustalonym zagadnieniu termosprężystości
Engineering Transactions, 1957 A quasi-steady state three-dimensional thermo-elastic problem The object here is to determine the state of stress in an elastic semi-space due to the action of a source of heat of intensity W, moving with a constant velocity v in the plane bounding the ...
Witold NOWACKI
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Minimizers of a variational problem inherit the symmetry of the domain
Electronic Journal of Differential Equations, 2012 We give a general framework under which the minimizers of a variational problem inherit the symmetry of the ambient space. The main technique used is the moving plane (or sliding) method.
Marcelo Montenegro, Enrico Valdinoci
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Decay and symmetry of positive solutions of elliptic systems in unbounded cylinders
Electronic Journal of Differential Equations, 2005 In this paper, we study the asymptotic behavior of positive solutions and apply the ``improved moving plane'' method to prove the symmetry of positive solutions of semilinear elliptic systems in unbounded cylinders.
Kuan-Ju Chen
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Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
3-D particle tracking in a two-photon microscope: application to the study of molecular dynamics in cells. [PDF]
Biophys J, 2005 Levi V, Ruan Q, Gratton E.
europepmc +1 more source