Results 91 to 100 of about 3,899,262 (296)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Digital Beamforming and Traffic Monitoring Using the new FSAR System of DLR [PDF]

open access: yes, 2007
In November 2006 the first X-band test flight of DLR’s new FSAR system has been performed successfully and in February 2007 the first flight campaign has been conducted for acquiring experimental multi-channel data of controlled ground moving targets. In
Moreira, Alberto   +6 more
core  

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Dual-Platform GMTI: First Results With The TerraSAR-X/TanDEM-X Constellation [PDF]

open access: yes, 2011
First ground moving target indication (GMTI) and parameter estimation results obtained with the German TerraSAR-X/TanDEM-X radar satellite constellation are presented and discussed.
Baumgartner, Stefan V., Krieger, Gerhard
core  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Optimal strategy selection approach of moving target defense based on Markov time game

open access: yesTongxin xuebao, 2020
For the problem that the existed game model was challenging to model the dynamic continuous characteristics of network attack and defense confrontation effectively,a method based on Markov time game was proposed to select the optimal strategy for moving ...
Jinglei TAN   +4 more
doaj   +2 more sources

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Binocular Based Moving Target Tracking for Mobile Robot

open access: yes, 2009
Moving target tracking is an important application of computer vision. A binocular based method is presented for mobile robot to track target reliably under the effect of occlusion, transform and rotation in unstructured environment.
Fan BJ(范保杰)   +3 more
core  

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