Results 81 to 90 of about 3,899,262 (296)

A Two-Layer Framework for Cooperative Standoff Tracking of a Ground Moving Target Using Dual UAVs

open access: yesDrones
Standoff tracking of a ground-moving target with a single fixed-wing unmanned aerial vehicle (UAV) is vulnerable to occlusions around the target, such as buildings and terrain, which can obstruct the line of sight (LOS) between the UAV and the target ...
Jing Chen   +7 more
doaj   +1 more source

How γ-secretase hits a moving target

open access: yeseLife, 2016
An improved understanding of the ways that amyloid-beta peptides are formed could help efforts to find a treatment for Alzheimer’s disease.
Charles R Sanders
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

The “moving targets” training algorithm [PDF]

open access: yes, 1990
A simple method for training the dynamical behavior of a neural network is derived. It is applicable to any training problem in discrete-time networks with arbitrary feedback. The method resembles back-propagation in that it is a least-squares, gradient-based optimization method, but the optimization is carried out in the hidden part of state space ...
openaire   +4 more sources

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Feasibility study of 4D-online monitoring of density gradients induced by lung cancer treatment using carbon ions

open access: yesFrontiers in Oncology
Tumor motion is a major challenge for scanned ion-beam therapy. In the case of lung tumors, strong under- and overdosage can be induced due to the high density gradients between the tumor- and bone tissues compared to lung tissues.
Claire-Anne Reidel   +23 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Implementing an IPv6 Moving Target Defense on a Live Network

open access: yes, 2012
The goal of our research is to protect sensitive communications, which are commonly used by government agencies, from eavesdroppers or social engineers.
Marchany, Randolph C.   +3 more
core  

Mountain grain in the Grisons Alps [PDF]

open access: yes
The mountain grain value chain represents traditional highland farming practices enhanced by innovative approaches to new production methods and marketing schemes.
Jaisli, Isabel, Forrer, Carmen
core   +1 more source

Moving target defense in Edge-Cloud systems: a systematic literature review

open access: yesJournal of Cloud Computing: Advances, Systems and Applications
The Edge-Cloud Computing paradigm has played a major role in the process of increasing the performance of services offered by IT companies. The goal is to merge both benefits of Cloud and Edge combined with the introduction of Internet of Things (IoT ...
Valentina Casola   +2 more
doaj   +1 more source

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