Results 51 to 60 of about 4,251,152 (284)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

CHAOS: An SDN-Based Moving Target Defense System [PDF]

open access: yes, 2017
Moving target defense (MTD) has provided a dynamic and proactive network defense to reduce or move the attack surface that is available for exploitation. However, traditional network is difficult to realize dynamic and active security defense effectively
Daochen Zha   +8 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Evolutionary based moving target cyber defense [PDF]

open access: yesProceedings of the Companion Publication of the 2014 Annual Conference on Genetic and Evolutionary Computation, 2014
A Moving Target (MT) defense constantly changes a system's attack surface, in an attempt to limit the usefulness of the reconnaissance the attacker has collected. One approach to this defense strategy is to intermittently change a system's configuration. These changes must maintain functionality and security, while also being diverse.
David J. John   +4 more
openaire   +2 more sources

On optimal search for a moving target [PDF]

open access: yes, 1997
The work of this thesis is concerned with the following problem and its derivatives. Consider the problem of searching for a target which moves randomly between n sites. The movement is modelled with an n state Markov chain.
Jordan, Benjamin Paul
core  

Fast GMTI Algorithm For Traffic Monitoring Based On A Priori Knowledge [PDF]

open access: yes, 2012
In this paper a fast a priori knowledge-based ground moving target indication and parameter estimation algorithm applicable to single- as well as to multi-channel synthetic aperture airborne radar data is presented.
Baumgartner, Stefan Valentin   +1 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

A rotational moving target defense solution for web servers [PDF]

open access: yes, 2018
Administrators of web servers fight a constant battle to keep their software current and secured from automated tools that roam the Internet looking for easy targets.
Bisinger, Steffanie
core  

Evaluating Deception and Moving Target Defense with Network Attack Simulation [PDF]

open access: yes, 2023
In the field of network security, with the ongoing arms race between attackers, seeking new vulnerabilities to bypass defense mechanisms and defenders reinforcing their prevention, detection and response strategies, the novel concept of cyber deception ...
Schotten, Hans-Dieter   +4 more
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy