Results 111 to 120 of about 34,044 (291)

Leveraging OpenSimMPLS: A simulation platform for GoS/MPLS networks in research and education

open access: yesSoftwareX
Open SimMPLS, an open-source simulator for Multiprotocol Label Switching (MPLS) networks, has been crucial in education, research, and industry for 20 years.
Manuel Domínguez-Dorado   +5 more
doaj   +1 more source

Unveiling relative lymphopenia and elevated monocyte‐to‐lymphocyte count as novel independent adverse prognostic factors in chronic myelomonocytic leukemia (CMML)—Proposal of the objective prognostic index for CMML (OPIC)

open access: yesHemaSphere, Volume 10, Issue 1, January 2026.
Abstract Chronic myelomonocytic leukemia (CMML) shows marked prognostic heterogeneity. Although leukocytosis is a recognized adverse prognostic factor, the contribution of its individual components remains insufficiently defined. In a cohort of 240 patients classified according to International Consensus Classification (ICC) and World Health ...
Xavier Calvo   +19 more
wiley   +1 more source

Metformin Downregulates the STAT Pathway and Reduces Bone Marrow Fibrosis in Primary Myelofibrosis Patients: Final Results of the Phase II FIBROMET Trial

open access: yesHematological Oncology, Volume 44, Issue 1, January 2026.
ABSTRACT Primary myelofibrosis (PMF) is a chronic myeloproliferative neoplasm characterized by the activation of the JAK‐STAT pathway. Previous evidence showed that metformin might be a possible therapeutic option for treating JAK2‐mediated myeloproliferative neoplasms.
Paula de Melo Campos   +11 more
wiley   +1 more source

MPLS中一种环路检测方法的研究

open access: yesGuangtongxin yanjiu, 2005
路径循环问题是影响多协议标签交换(MPLS)网络质量的主要因素之一,但是目前基于异步传输模式(ATM)的MPLS却缺乏有效的环路检测措施。文章首先介绍了MPLS中解决环路问题的各种方法,然后结合MPLS兼容ATM的信元特点,提出了一种利用ATM适配层中的AAL5数据单元对分组在转发过程中进行环路检测的方法。
侯睿, 孙军强, 丁攀峰
doaj  

MDS/MPN With SF3B1 Mutation and Thrombocytosis but Without Ring Sideroblasts

open access: yes
American Journal of Hematology, Volume 101, Issue 1, Page 129-130, January 2026.
Biswadip Hazarika, Barbara J. Bain
wiley   +1 more source

A De Novo Splicing Mutation of SRP72 in Bone Marrow Failure Syndrome Type 1: Case Report and Review of the Literature

open access: yesMolecular Genetics &Genomic Medicine, Volume 14, Issue 1, January 2026.
This study reports a rare case of bone marrow failure syndrome type 1 (BMFS1) caused by a novel de novo splicing mutation (c.1502+1G>A) in the SRP72 gene. The 6‐year‐old patient presented with aplastic anemia and pancytopenia. Genetic analysis identified the mutation, which was absent in both parents, confirming its de novo origin.
Wang Xiangwen   +3 more
wiley   +1 more source

Bone marrow histology in CALR mutated thrombocythemia and myelofibrosis: results from two cross sectional studies in 70 newly diagnosed JAK2/MPL wild type thrombocythemia patients [PDF]

open access: hybrid, 2019
Jan Michiels   +8 more
openalex   +1 more source

Clinical test cases for commissioning, QA, and benchmarking of model‐based dose calculation algorithms in 1⁹2Ir HDR gynecologic tandem and ring brachytherapy

open access: yesMedical Physics, Volume 53, Issue 1, January 2026.
Abstract Purpose To develop clinically relevant test cases for commissioning Model‐Based Dose Calculation Algorithms (MBDCAs) for 192Ir High Dose Rate (HDR) gynecologic brachytherapy following the workflow proposed by the TG‐186 report and the WGDCAB report 372.
Vasiliki Peppa   +6 more
wiley   +1 more source

基于T-MPLS的路由与波长分配问题研究

open access: yesGuangtongxin yanjiu, 2009
文章介绍了光传送网承载传送多协议标签交换(T-MPLS)的结构,分析了解决基于T-MPLS的路由与波长分配(RWA)问题所采用的算法的类型。随后,将基于T-MPLS的RWA问题分为路由选择和波长分配两个子问题,结合T-MPLS技术的特点分别从支持流量工程、多域情况、支持组播和支持区分业务等方面进行研究。
梁思远, 赵季红, 曲桦
doaj  

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