Results 141 to 150 of about 10,263 (209)

Exposure–Response Analyses of Ropeginterferon Alfa‐2b in Essential Thrombocythemia

open access: yesThe Journal of Clinical Pharmacology, Volume 66, Issue 10, October 2026.
Abstract Ropeginterferon alfa‐2b is a new‐generation interferon therapy for the treatment of myeloproliferative neoplasms (MPNs), including essential thrombocythemia (ET). This investigation was designed to characterize its population pharmacokinetics–pharmacodynamics (PopPK‐PD) and delineate exposure–response (E‐R) relationships in ET. A population PK
Albert Qin   +20 more
wiley   +1 more source

MPLS TUNNELS

open access: yes
Za ovaj diplomski rad izabrana je tema "MPLS tuneli". U radu je obrađena teorija MPLS tehnologije, njezina svrha i praktična primjena u mrežnim sustavima.
Dujmović, Matej
core   +2 more sources

Clinicopathologic Characteristics of Somatic TP53 Mutations in Philadelphia Chromosome–Negative Myeloproliferative Neoplasms: A Systematic Review

open access: yeseJHaem, Volume 7, Issue 5, October 2026.
ABSTRACT Background TP53 mutations (TP53m) are uncommon in chronic‐phase Ph–negative myeloproliferative neoplasms but become enriched in myelofibrosis (MF) and accelerated/blast phase myeloproliferative (AP/BP‐MPN). Their prevalence, allelic distribution, and phase‐stratified outcomes have not been systematically synthesized.
Mahmood Aldapt   +9 more
wiley   +1 more source

Survival outcomes and treatment patterns in myelofibrosis in the JAK inhibitor era

open access: yesBritish Journal of Haematology, Volume 209, Issue 4, Page 1715-1724, October 2026.
Summary Data on real‐world survival and treatment patterns in large, unselected myelofibrosis (MF) cohorts remain limited. We analysed 1649 patients with MF diagnosed from 2010 onwards and included in the Spanish Myelofibrosis Registry across 64 centres. Janus kinase (JAK) inhibitors were administered to approximately half of the patients.
Juan‐Carlos Hernández‐Boluda   +35 more
wiley   +1 more source

Haematopoietic Cells Deficient for Calreticulin or Expressing Its Oncogenic Variants Maintain Functional Antigen Presentation

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 19, October 2026.
ABSTRACT Intact antigen presentation in cancer cells is a key prerequisite for endogenous anticancer T cell responses and a starting point for immunotherapy. Calreticulin was postulated as a chaperone and integral part of the peptide‐loading complex of MHC‐I.
Maria Höhrhan   +8 more
wiley   +1 more source

Estudio de factibilidad para el diseño de una red MPLS como backbone de internet para brindar servicios de internet fijo y móvil en relación al crecimiento poblacional del Ecuador hasta el año 2021

open access: yes, 2017
La gran mayoría de empresas de telecomunicaciones en Ecuador utilizan redes IP con el protocolo MPLS, como ejemplo en la infraestructura de telecomunicaciones de los proveedores de servicios de Internet utilizan redes IP/MPLS con tecnología del ...
Cueva Soto, Darwin Stalin
core  

The Role of Labour Market Institutions in Shaping Euro Area Monetary Policy Transmission

open access: yesOxford Bulletin of Economics and Statistics, Volume 88, Issue 5, Page 919-936, October 2026.
ABSTRACT We examine how labour market institutions shape monetary policy transmission in euro area countries. A theoretical model suggests that higher union density flattens the Phillips curve, amplifying output responses while dampening the inflation effects of monetary shocks. This is empirically confirmed using an interacted panel VAR.
Maximilian Boeck, Christian Glocker
wiley   +1 more source

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