Results 31 to 40 of about 12,309 (198)

Viroporins of Mpox Virus

International Journal of Molecular Sciences, 2023
Mpox or monkeypox virus (MPXV) belongs to the subclass of Poxviridae and has emerged recently as a global threat. With a limited number of anti-viral drugs available for this new virus species, it is challenging to thwart the illness it begets. Therefore, characterizing new drug targets in the virus may prove advantageous to curbing the disease.
Kingshuk Basu, Miriam Krugliak, Isaiah T. Arkin   +2 more
openaire   +2 more sources

Epidemiological characteristics and transmission dynamics of mpox in Bujumbura, Burundi, 2024

Journal of Infection and Public Health
Background: In Africa, the transmission of Monkeypox (mpox), especially in countries that were initially unaffected, including Burundi, is still inefficiently reported.
John Otokoye Otshudiema, Liliane Nkengurutse, Godefroid Kamwenubusa, Issa Diallo, Aimable Sibomana, Odette Nsavyimana, Stanislas Harakandi, Jean Claude Mbonicura, Jean Claude Nkurunziza, Fidèle Cishahayo, Dieudonné Niyongere, Bonite Havyarimana, Déo Simbarariye, Marc Nimburanira, Bosco Ntiranyibagira, Armel Bitaneza, Quentine Irankunda, Alice Bella Kanyange, Benoit Nikoyandemye, Stany Nduwimana, Freddy Nyabenda, Olivier Kamatari, Sonia Irambona, Alexis Niyomwungere, Jim Thierry Ntwari, Abdoulaye Bousso, Samuel Boland, Otim Patrick Cossy Ramadan, Rosamund Lewis, Alimuddin Zumla, Joseph Nyandwi   +30 more
doaj   +1 more source

Knowledge about, attitudes toward and acceptance and predictors of intention to receive the mpox vaccine among cancer patients in China: A cross-sectional survey

Human Vaccines & Immunotherapeutics
This study aimed to investigate the knowledge about, attitudes toward, and acceptance and predictors of receiving the mpox vaccine among Chinese cancer patients. Patients were selected using a convenience sampling method.
Jie Ding, Xing-Chen Liu, Jing Hong, Qing-Mei Zhang, Xiao-Wan Xu, Yi-Qun Liu, Chao-Qin Yu   +6 more
doaj   +1 more source

Mpox vaccination basics [PDF]

Updated March 22, 2023Mpox (formerly known as monkeypox) is caused by a virus that is related to the virus that causes smallpox. JYNNEOS is a 2-dose vaccine developed to protect against mpox and smallpox infections.

core   +8 more sources

Behavioral Intention of Receiving Monkeypox Vaccination and Undergoing Monkeypox Testing and the Associated Factors Among Young Men Who Have Sex With Men in China: Large Cross-Sectional Study

JMIR Public Health and Surveillance
BackgroundThe worldwide human monkeypox (mpox) outbreak in 2022 mainly affected men who have sex with men (MSM). In China, young men who have sex with men (YMSM) were at a potential high risk of mpox infection due to their sexual ...
Sitong Luo, Kedi Jiao, Yuhang Zhang, Yutong Xu, Jingtao Zhou, Siwen Huang, Yan Li, Yongkang Xiao, Wei Ma, Lin He, Xianlong Ren, Zhen Dai, Jiaruo Sun, Qingyu Li, Feng Cheng, Wannian Liang   +15 more
doaj   +1 more source

Mpox knowledge and vaccination hesitancy among healthcare workers in Beijing, China: A cross-sectional survey

Vaccine: X
Background: Mpox, one of the most serious threats to global health, is now being seen in small but rising numbers in Beijing, China. Our study aimed to investigate healthcare workers’ (HCWs) knowledge of Mpox and to explore reasons associated with their ...
Yuan Yang, Weijie Zhang, Baihui Han, Han Meng, Jiaqi Wang, Ke Wu, Leiwen Fu, Bingyi Wang, Xiaohong Jiang, Qian Li, Zhiyuan Xu, Ye Zhang, Xiao Qi, Huachun Zou   +13 more
doaj   +1 more source

Perception of and Vaccine Readiness towards Mpox among Men Who Have Sex with Men Living with HIV in China: A Cross-Sectional Study

Vaccines, 2023
Background: Men who have sex with men (MSM) living with HIV make up the majority of cases in the current Mpox outbreak. We aimed to investigate the perception of and vaccine readiness towards Mpox among MSM living with HIV in China.
Leiwen Fu, Yinghui Sun, Yuwei Li, Bingyi Wang, Luoyao Yang, Tian Tian, Xinsheng Wu, Xin Peng, Qi Liu, Yuanyi Chen, Yi-Fan Lin, Hui Li, Xiaojun Meng, Huachun Zou   +13 more
doaj   +1 more source

History of sexually transmitted infections among mpox cases in the 2022 outbreak in Spain. [PDF]

HIV Med
Abstract Objective The aim was to describe the history of sexually transmitted infections (STIs) among adult mpox men cases and to analyse sociodemographic and epidemiological characteristics according to the presence or absence of any STI diagnosed 1 or 6 months previous to mpox diagnosis during the 2022 outbreak in Spain.
March-Yagüe A, Toledo D, Díaz A, Godoy P, Pérez-Martínez O, Pericas C, Sanchez-Migallon A, Chirlaque MD, Ospina J, Grau M, Roig F, Domínguez A, and the MONKPOX‐ESP22 Subproject 3.2 Working Group.   +12 more
europepmc   +2 more sources

A Fatal Case of Monkeypox-Associated Encephalitis in a Non–HIV-Infected Patient

Critical Care Explorations
BACKGROUND:. Mpox, formerly known as monkeypox, is an infectious disease caused by the mpox virus. Systemic involvement is rare and mpox-associated meningoencephalitis is an uncommon clinical presentation.
Cristina Lopez, MD, Rafael Sanchez-Sanchez, MD, Diana Corona, PhD, Ana Belen Perez, PhD, Francisco Bravo, MD, Maria de Alba, MD, Antonio Bracero, MSN, Cristina Cazorla, MD, Ana Vázquez, PhD, Maria Paz Sánchez-Seco, PhD, Ana Negredo, PhD, Ulises Gómez-Pinedo, PhD, Luis Martinez-Martinez, PhD, Julian Torre-Cisneros, PhD, Carmen de la Fuente, MD   +14 more
doaj   +1 more source

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

Advanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang, Shuqin Xu, Zixuan Zhang, Chenwen Wan, Xiaoqin Wang, Peihua Wang, Huini Yang, Tianxiao Huang, Yijia Yuan, Faiza Atique, Rui Yang, Yingli He, Zhijun Liu   +12 more
wiley   +1 more source