Results 51 to 60 of about 13,420 (218)
We developed four candidate mRNA vaccine antigens based on conserved sequences of MPXV A35R and M1R proteins. Our findings demonstrate that the MV2 vaccine possesses favorable immunogenicity and prophylactic potential against MPXV and VACV infections, positioning it as a promising clinical candidate for MPXV prevention.
Cong Tang +14 more
wiley +1 more source
Incubation period and serial interval of mpox for the 2022 global outbreak compared to historical (pre-2022) estimates [PDF]
Better understanding changes to the transmission dynamics of mpox requires comparing recent estimates of key epidemiological parameters, the incubation period and serial interval, with historical data.
Akhmetzhanov, Andrei +6 more
core +2 more sources
Informal PrEP use in Greece: The long, hard road to formal programmatic implementation
Abstract Objectives Pre‐exposure prophylaxis (PrEP) with antiretroviral drugs (ARVs) is a highly effective HIV prevention strategy. Although the European Medicines Agency approved oral PrEP in 2016 and the World Health Organization (WHO) has since recommended simplified and person‐centred delivery models, implementation remains inconsistent across ...
Konstantinos Protopapas +3 more
wiley +1 more source
Humoral epitope dominance and immune imprinting by SARS‐CoV‐1 and SARS‐CoV‐2 vaccines
We investigated Modified Vaccinia Ankara (MVA) vaccine candidates expressing the SARS‐CoV‐1 or SARS‐CoV‐2 Spike, as a primary or booster immunization, for their ability to induce antibodies targeting different epitopes on the SARS‐CoV‐2 RBD and broad cross‐reactive or cross‐neutralizing responses in C57BL/6 and antibody humanized (Ig‐humanized) mice ...
Deborah L Burnett +17 more
wiley +1 more source
Public trust and cooperation in infectious disease control rest on three pillars: engagement, vaccine communication, and data presentation. Together, these foundations support resilient and inclusive public health responses to misinformation and uncertainty.
Sheena Cruickshank +2 more
wiley +1 more source
Experiences of mpox illness and case management among cis and trans gay, bisexual and other men who have sex with men in England: a qualitative study [PDF]
Background: The 2022–2024 global mpox outbreak, occurring primarily in the sexual networks of gay, bisexual and other men who have sex with men (GBMSM), has not been accompanied by a focus on patient perspectives of illness.
T. Charles Witzel +13 more
openalex +3 more sources
Wei et al. report that MPXV infection induces aerobic glycolysis, a process mediated by the viral protein I3 through lysine crotonylation at its K102 residue. The acetyltransferase MYST1 catalyzes the crotonylation of I3 to inhibit the ubiquitin‐mediated degradation of WDR26.
Pengjun Wei +12 more
wiley +1 more source
This review examines the use of fluorescent nanodiamonds (FNDs) in lateral flow assays (LFAs) for advanced diagnostics. FNDs offer superior photostability and biocompatibility compared to traditional labels. The review covers FND synthesis, and integration with detection systems to enhance performance.
Jihoon Shin +10 more
wiley +1 more source
Mpox in people with past infection or a complete vaccination course : a global case series [PDF]
We thank the individuals with mpox who agreed to allow their medical team to share their data; the medical staff who looked after the participants; and all the listed contributors for their efforts in collecting the data.Background: Since May, 2022, a ...
Bell, Elizabeth +20 more
core +4 more sources
Severe Mpox Proctitis Complicated by Bowel Obstruction
Hasan Saleh +8 more
openalex +1 more source

