Results 61 to 70 of about 1,337,091 (204)

Characteristics of confirmed mpox cases among clinical suspects: A prospective single-centre study in Belgium during the 2022 outbreak [PDF]

open access: yes, 2023
Background: The presentation of mpox clade IIb during the 2022 outbreak overlaps with a range of other diseases. Understanding the factors associated with mpox is important for clinical decision making.
Patrick Soentjens   +47 more
core   +1 more source

Exploring monkeypox virus proteins and rapid detection techniques

open access: yesFrontiers in Cellular and Infection Microbiology
Monkeypox (mpox) is an infectious disease caused by the mpox virus and can potentially lead to fatal outcomes. It resembles infections caused by viruses from other families, challenging identification.
Kamila Sagdat   +2 more
doaj   +1 more source

Application of Artificial Intelligence Techniques for Monkeypox: A Systematic Review

open access: yesDiagnostics, 2023
Monkeypox or Mpox is an infectious virus predominantly found in Africa. It has spread to many countries since its latest outbreak. Symptoms such as headaches, chills, and fever are observed in humans.
Krishnaraj Chadaga   +6 more
doaj   +1 more source

Molecular glues: Recent advances in cereblon substrate identification and mechanistic insights

open access: yesSmart Molecules, EarlyView.
Molecular glues exert diverse core biological functions by inducing or stabilizing protein–protein interactions, extending far beyond the traditional scope of targeted protein degradation. Key breakthroughs include expanded cereblon substrate recognition, sustained G protein‐coupled receptor megacomplex signaling, and the first orthosteric molecular ...
Qingyun Guan   +5 more
wiley   +1 more source

Evidence of Mpox clade IIb infection in primary human alveolar epithelium

open access: yesEmerging Microbes and Infections
Monkeypox virus (Mpox) has been recognized for causing distinct skin lesions and is primarily transmitted through skin and sexual contact. To date, the transmissibility and pathogenesis of the Mpox virus in distal human lung has never been completely ...
Thanaphon Namporn   +13 more
doaj   +1 more source

Putting Rodents at the Center of One Health Programs: A Narrative Synthesis

open access: yesIntegrative Zoology, EarlyView.
Rodents link human, animal, and environmental health across diverse ecosystems. Rodent diversity underpins both zoonotic disease risk and ecosystem function. Environmental change reshapes rodent communities and spillover dynamics. Rodents act as reservoirs, amplifiers, and sentinels of emerging pathogens.
Steven R. Belmain
wiley   +1 more source

A comparative analysis of cell death signalling in RNA and DNA virus infections and potential inhibitory strategies

open access: yesThe FEBS Journal, EarlyView.
RNA and DNA viruses can manipulate host cell death through various mechanisms. RNA viruses (H1N1, SARS‐CoV‐2) induce acute apoptosis, necroptosis, and pyroptosis to promote rapid viral transmission and epithelial barrier damage. In contrast, DNA viruses (HSV‐1, EBV) regulate these mechanisms to sustain a lytic‐latency cycle, evade immune response and ...
Panagiotis Keramidas   +4 more
wiley   +1 more source

The Mpox vaccine (JYNNEOS vaccine) [PDF]

open access: yes
Mpox (formerly known as monkeypox) is caused by a virus that is related to the virus that causes smallpox. JYNNEOS is a 2-dose vaccine that was developed to protect against both mpox and smallpox. People need to get both doses of the vaccine for the best

core   +2 more sources

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

open access: yesAdvanced Science, Volume 13, Issue 62, 9 November 2026.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang   +12 more
wiley   +1 more source

A new attenuated and highly immunogenic orthopoxvirus vaccine protects against mpox in mice and macaques

open access: yesnpj Vaccines
Shortly after 2022, mpox again becomes a public health emergency of international concern as declared by the World Health Organization on August 14, 2024.
Fengwen Xu   +23 more
doaj   +1 more source

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