Altered medial prefrontal cortex and dorsal raphé activity predict genotype and correlate with abnormal learning behavior in a mouse model of autism-associated 2p16.3 deletion. [PDF]
2p16.3 deletion, involving NEUREXIN1 (NRXN1) heterozygous deletion, substantially increases the risk of developing autism and other neurodevelopmental disorders.
Hughes RB +4 more
europepmc +3 more sources
Expression and characterization of mouse prolactin (mPRL) in CHO dhfr- cells [PDF]
Background Prolactin (PRL) is a peptide hormone related to innumerous physiological functions such as lactation, reproduction, osmotic and immune regulation [1]. In order to evaluate new drugs many tests are conducted in mouse models. Use of prolactin from different origin in mouse model can result in differences in biological activities [2].
Suzuki, Miriam +5 more
openaire +2 more sources
Macroprolactinemia in a Patient with Invasive Macroprolactinoma: A Case Report and Minireview [PDF]
Background. Macroprolactin, the high-molecular prolactin isoform, is considered to be an inactive in vivo product with extrapituitary origin. Patients with macroprolactinemia are usually asymptomatic, with negative pituitary imaging. Based on these data,
Atanaska Elenkova +5 more
doaj +2 more sources
Chronic social defeat stress leads to the development of anxiety- and depression-like states in male mice and is accompanied by numerous molecular changes in brain.
Dmitry A. Smagin +5 more
doaj +2 more sources
Síntese e caracterização de prolactina de camundongo (mPRL) e deu seu análogo (S177D-mPRL) [PDF]
A prolactina é um neurohormônio que faz parte da superfamília das citocinas e está envolvida em inúmeros processos biológicos. Devido à sua ação endócrina, autócrina e parácrina, a prolactina está muitas vezes relacionada ao desenvolvimento de patogenias
Miriam Fussae Suzuki +1 more
openaire +2 more sources
Building a Bridge Between Ambient MS and LC-MS by Non-Exhaustive Microdesorption. [PDF]
A sequential analysis strategy was developed to integrate rapid ambient mass spectrometry (MS) screening with LC‐MS confirmation using a single solid‐phase microextraction (SPME) device. The approach involves an initial non‐exhaustive microdesorption for ambient MS screening, followed by a second desorption for LC‐MS confirmation of only the disputed ...
Zhou W, Pawliszyn J.
europepmc +3 more sources
Medial patellofemoral ligament reconstruction using nonresorbable sutures yields comparable outcomes to reconstruction with a pedicled quadriceps tendon autograft when performed in addition to bony risk factor correction. [PDF]
Abstract PurposeTo evaluate the results for reconstruction of the medial patellofemoral ligament using synthetic nonresorbable sutures (S‐MPFL‐R) in comparison to MPFL‐R using quadriceps tendon autograft (QT‐MPFL‐R) in patients undergoing simultaneous correction of anatomic risk factors for lateral patellar instability (LPI) at a minimum of 2 years of ...
Milinkovic DD, Zimmermann F, Balcarek P.
europepmc +2 more sources
Multiple cell types in the oviduct express the prolactin receptor. [PDF]
Abstract Little is known about the physiological role of prolactin in the oviduct. Examining mRNA for all four isoforms of the prolactin receptor (PRLR) in mice by functional oviduct segment and stage of the estrous cycle, we found short form 3 (SF3) to be the most highly expressed, far exceeding the long form (LF) in highly ciliated areas such as the ...
Radecki KC +6 more
europepmc +2 more sources
Novel dense membranes were fabricated by blending poly(ether-b-amid), Pebax 1657, as the matrix and a poly(amidoamine) dendritic polymer (PAMAM), as the modifier, to evaluate CO2/CH4 gases separation.
Atousa Tayebi +2 more
doaj +1 more source
Prevalence of Macroprolactinaemia by Polyethylene Glycol Precipitation Method: A Cross-sectional Study [PDF]
Introduction: Macroprolactin, an immunoreactive molecule resulting from association of monomeric Prolactin (mPRL) and immunoglobulin G is a significant cause of misdiagnosis, unnecessary radiological investigation and treatment for ...
RAGHUNATH BHATTACHARYYA +4 more
doaj +1 more source

