Results 71 to 80 of about 28,896 (199)
ABSTRACT Host genetic factors may contribute to COVID‐19 severity. To identify genetic variants influencing COVID‐19 severity progression, whole‐exome sequencing was performed, followed by an exome‐wide association study on 191 hospitalized patients categorized into three severity groups.
Doris Repušić +7 more
wiley +1 more source
Viral Detection and Clinical Disease Features in Pediatric Chronic Rhinosinusitis
ABSTRACT Objectives Chronic rhinosinusitis (CRS) results from complex host‐environment interactions with microbiome dysbiosis and viral infections postulated to drive inflammation and anatomic remodeling. This study investigates the impact of viral presence on pediatric sinonasal disease and clinical outcomes.
Mary C. Wilding +7 more
wiley +1 more source
ABSTRACT Recent advances in the numerical solution of fractional partial differential equations have yielded promising results. In particular, the Shifted Grünwald–Letnikov (SGL) approach allows for a generalization of the traditional finite difference method to the context of fractional differential equations.
Pedro Victor Serra Mascarenhas +1 more
wiley +1 more source
Among 80 patients with locally advanced NSCLC receiving durvalumab after CCRT, 44 patients (55%) did not complete 12 months of treatment. Lower A/G ratio and higher RDW‐SD before durvalumab initiation may serve as exploratory signals for non‐completion, closer monitoring, and supportive care planning.
Masaaki Kotake +4 more
wiley +1 more source
Can we boost vaccine responses in older adults? In a double‐blind, randomised, placebo‐controlled pilot study (n = 40, > 65 years), spermidine supplementation (6 mg/day, 13 weeks) was safe and significantly improved immune responses following a 3rd SARS‐CoV‐2 vaccine dose.
Ghada Alsaleh +25 more
wiley +1 more source
Morquio syndrome (MPV IV)--a case report.
A child, of normal intelligence, belonging to a nonconsanguineous marriage was diagnosed as MPS type IV the so called Morquio syndrome. Despite mild corneal cloudiness no other ophthalmological abnormalities were observed. Reilly granules in the leukocytes and abnormal mucopolysaccharides in urine confirmed the diagnosis.
openaire +2 more sources
Summary ETV6‐related thrombocytopenia (ETV6‐RT) is an inherited platelet disorder caused by germline ETV6 variants. Despite recent progress, the mechanisms underlying platelet dysfunction in ETV6‐RT remain unclear. We investigated 12 patients from six families using functional assays, electron microscopy, quantitative proteomics and cytoskeletal ...
Ivan P. Tesakov +15 more
wiley +1 more source
D. Mannaerts +5 more
semanticscholar +1 more source
ABSTRACT Haemophilia A (HA) is an X‐linked bleeding disorder caused by factor VIII (FVIII) deficiency, treated with FVIII infusions or, more recently, Emicizumab subcutaneously. Although Emicizumab is safe and effective, FVIII is still required for severe bleeding, trauma, or surgery, and few studies have compared these prophylactic options in ...
Alessia Cottonaro +10 more
wiley +1 more source

