Results 91 to 100 of about 82,070 (285)

Online adaptive radiotherapy for head and neck cancers on the MR linear Accelerator: Introducing a novel modified Adapt-to-Shape approach

Clinical and Translational Radiation Oncology, 2022
Introduction: The Elekta Unity MR-Linac (MRL) has enabled adaptive radiotherapy (ART) for patients with head and neck cancers (HNC). Adapt-To-Shape-Lite (ATS-Lite) is a novel Adapt-to-Shape strategy that provides ART without requiring daily clinician ...
Amit Gupta, Alex Dunlop, Adam Mitchell, Dualta McQuaid, Simeon Nill, Helen Barnes, Kate Newbold, Chris Nutting, Shreerang Bhide, Uwe Oelfke, Kevin Joseph Harrington, Kee Howe Wong   +11 more
doaj   +1 more source

Endoscopic ultrasound in the staging of gastrointestinal luminal malignancies [PDF]

, 2013
Endoscopic ultrasound (EUS) is an important tool in the staging of gastrointestinal cancers. This review highlights the use of EUS in the staging of gastrointestinal luminal malignancies and compares the performance of EUS with other imaging modalities ...
Azzopardi, Neville
core  

The Role of Daily Adaptive Stereotactic MR-Guided Radiotherapy for Renal Cell Cancer

Cancers, 2020
Simple Summary Standard treatment for localized renal cell carcinoma (RCC) is surgery. Stereotactic radiotherapy given in a few high dose fractions is a promising treatment for this indication and could be an alternative option for patients unsuitable ...
S. Tetar, O. Bohoudi, S. Senan, M. Palacios, S. Oei, A. V. Wel, B. Slotman, R. V. Moorselaar, F. Lagerwaard, A. Bruynzeel   +9 more
semanticscholar   +1 more source

PROTAC‑Mediated HMGCR Depletion Reprograms Lipid Metabolism in Breast Cancer to Potentiate Photoimmunotherapy via Ferroptosis

Advanced Science, EarlyView.
This work introduces a study that identifies HMGCR as a novel target in TNBC and develops a light‐gated PROTAC nanomedicine. Upon irradiation, this agent selectively degrades HMGCR, reprogramming lipid metabolism to induce ferroptosis and potent antitumor immunity, thereby significantly enhancing photoimmunotherapy efficacy.
Tong Su, Guang Li, Yudong Guan, Qi Tian, Youzhi Qi, Yanqiu Zhang, Wenqian Wei, Xinxin Duan, Jiaxin Rui, Hongyan Zhu, Zengping Lin, Changchuan Xie, Zheni Xu, Yaying Wu, Xin Peng, Zhenjie Wang, Kun Chen, Xiaoyan Xin, Bing Zhang   +18 more
wiley   +1 more source

A body mass index-based method for “MR-only” abdominal MR-guided adaptive radiotherapy

Zeitschrift für Medizinische Physik
Purpose: Dose calculation for MR-guided radiotherapy (MRgRT) at the 0.35 T MR-Linac is currently based on deformation of planning CTs (defCT) acquired for each patient.
Carolin Rippke, C. Katharina Renkamp, Christiane Stahl-Arnsberger, Annette Miltner, Carolin Buchele, Juliane Hörner-Rieber, Jonas Ristau, Jürgen Debus, Markus Alber, Sebastian Klüter   +9 more
doaj   +1 more source

Magnetic resonance imaging for localization of prostate cancer in the setting of biochemical recurrence [PDF]

, 2016
The clinical suspicion of local recurrence of prostate cancer after radical treatment is based on the onset of biochemical failure. The use of multiparametric magnetic resonance imaging (MRI) for prostate cancer has increased over recent years, mainly ...
Barchetti, Flavio, Cardone, Gianpiero, Catalano, Carlo, Colarieti, Anna, Grompone, Marcello Domenico, Panebianco, Valeria, Salvo, Vincenzo   +6 more
core   +1 more source

MR-Guided Adaptive Radiotherapy in Localized Prostate Cancer

Technology in Cancer Research & Treatment
MR-guided radiotherapy (MRgRT) is novel treatment modality in Radiation Oncology that could allow a higher precision and tolerability of Radiation Treatments. This modality is possible due to dedicated systems consisting of a MR scanner mounted on a conventional linac and software that permit daily online treatment plan adaptation. Prostate cancer (PC)
Andrea Gaetano Allegra, Luca Nicosia, Michele Rigo, Nicola Bianchi, Riccardo Filippo Borgese, Antonio De Simone, Niccolò Giaj-Levra, Davide Gurrera, Stefania Naccarato, Edoardo Pastorello, Francesco Ricchetti, Gianluisa Sicignano, Ruggero Ruggieri, Filippo Alongi   +13 more
openaire   +3 more sources

Safety and Feasibility of Laparoscopic and Endoscopic Cooperative Surgery With Endoscopic Submucosal Dissection for Large Superficial Non‐Ampullary Duodenal Epithelial Tumors

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background and Aims Endoscopic submucosal dissection (ESD) for large superficial non‐ampullary duodenal epithelial tumors (SNADETs) poses substantial technical challenges, primarily because of a heightened risk of adverse events (AEs). Laparoscopic and endoscopic cooperative surgery (D‐LECS) was introduced to address these risks, with recent ...
Masaru Hayami, Shoichi Yoshimizu, Naoki Miyazaki, Shintaro Yamamoto, Hiroyuki Yamamoto, Motonari Ri, Rie Makuuchi, Tomoyuki Irino, Manabu Takamatsu, Souya Nunobe   +9 more
wiley   +1 more source

Daily adaptive radiotherapy for patients with prostate cancer using a high field MR-linac: Initial clinical experiences and assessment of delivered doses compared to a C-arm linac

Clinical and Translational Radiation Oncology, 2020
Introduction: MR-guided adapted radiotherapy (MRgART) using a high field MR-linac has recently become available. We report the estimated delivered fractional dose of the first five prostate cancer patients treated at our centre using MRgART and compare ...
Alex Dunlop, Adam Mitchell, Alison Tree, Helen Barnes, Lorna Bower, Joan Chick, Edmund Goodwin, Trina Herbert, Rebekah Lawes, Helen McNair, Dualta McQuaid, Jonathan Mohajer, Rahul Nilawar, Angela Pathmanathan, Gillian Smith, Ian Hanson, Simeon Nill, Uwe Oelfke   +17 more
doaj   +1 more source

Magnetic resonance guided adaptive stereotactic body radiotherapy for lung tumors in ultracentral location: the MAGELLAN trial (ARO 2021-3)

Radiation Oncology, 2022
Background Stereotactic Body Radiotherapy (SBRT) is a standard treatment for inoperable primary and secondary lung tumors. In case of ultracentral tumor location, defined as tumor contact with vulnerable mediastinal structures such as the proximal ...
Sebastian Regnery, Jonas Ristau, Fabian Weykamp, Philipp Hoegen, Simon David Sprengel, Katharina Maria Paul, Carolin Buchele, Sebastian Klüter, Carolin Rippke, Claudia Katharina Renkamp, Moritz Pohl, Jan Meis, Thomas Welzel, Sebastian Adeberg, Stefan Alexander Koerber, Jürgen Debus, Juliane Hörner-Rieber   +16 more
doaj   +1 more source