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Prone Breast Radiotherapy on the MR-Linac: A Technical Note on Skin-Couch Contact Dose Effects. [PDF]

J Med Radiat Sci
This retrospective planning study evaluated the dosimetric effects of skin‐couch contact during prone APBI on a 1.5 T MR‐Linac by comparing treatment plans calculated with and without a magnetic field. While the presence of the magnetic field increased overall superficial skin dose, it consistently reduced dose at the skin‐couch contact region ...
Brown K, Smith D, Matthews K, Lye J, McDermott L, Chao M, Foroudi F, Wright C.   +7 more
europepmc   +2 more sources

Repeatability and reproducibility of MRI-derived radiomics on a 0.35 T MR-Linac using a tissue-mimicking phantom [PDF]

Physics and Imaging in Radiation Oncology
Background and purpose: Magnetic resonance–guided radiotherapy provides real-time soft-tissue–based targeting during dose delivery. Beyond image guidance, magnetic resonance linear accelerator (MR-Linac) systems offer new opportunities for developing ...
Florian Collard, Fanny Herault, Ludovic Vanquin, Anne-Laure Gagez, Alain Loussert, Dominique Collard, David Pasquier   +6 more
doaj   +2 more sources

Daily adaptive radiotherapy for patients with prostate cancer using a high field MR-linac: Initial clinical experiences and assessment of delivered doses compared to a C-arm linac

Clinical and Translational Radiation Oncology, 2020
Introduction: MR-guided adapted radiotherapy (MRgART) using a high field MR-linac has recently become available. We report the estimated delivered fractional dose of the first five prostate cancer patients treated at our centre using MRgART and compare ...
Robert Adam Mitchell, Helen A McNair, Alison Tree   +2 more
exaly   +3 more sources

Evaluating participant experiences and tolerability with MR Linac imaging [PDF]

Technical Innovations & Patient Support in Radiation Oncology
Introduction: Magnetic Resonance Image Guided Radiotherapy (MRIgRT) integrates MRI with a linear accelerator to enable adaptive treatment delivery. While technical feasibility is well established, patient experience during MR Linac imaging, especially ...
Jayde Nartey, Helen A. McNair, Katie Biscombe, Sophie E. Alexander, Charlotte Cherry, Cynthia Eccles, Trina Herbert, Shaista Hafeez, Kelly Jones, Francesca Mason, Simeon Nill, Hosna Mohammad, Kian Morrison, Bethany Williams, Robert Huddart   +14 more
doaj   +2 more sources

Long-term performance evaluation of a 1.5T MR-Linac using statistical process control techniques [PDF]

Radiation Oncology
Background The integration of magnetic resonance imaging with linear accelerators (Linacs) enhances adaptive radiotherapy by providing real-time imaging for improved treatment precision.
Qing Xiao, Mengdie Shen, Guangjun Li, Shipai Zhu, Jinrong He, Qiang Wang, Guyu Dai, Hang Yu, Jialu Lai, Renming Zhong, Sen Bai   +10 more
doaj   +2 more sources

Impact of magnetic resonance-guided versus conventional radiotherapy workflows on organ at risk doses in stereotactic body radiotherapy for lymph node oligometastases

Physics and Imaging in Radiation Oncology, 2022
Background and purpose: Magnetic resonance (MR)-linac delivery is expected to improve organ at risk (OAR) sparing. In this study, OAR doses were compared for online adaptive MR-linac treatments and conventional cone beam computed tomography (CBCT)-linac ...
Anita M. Werensteijn-Honingh, Petra S. Kroon, Dennis Winkel, J. Carlijn van Gaal, Jochem Hes, Louk M.W. Snoeren, Jaleesa K. Timmer, Christiaan C.P. Mout, Gijsbert H. Bol, Alexis N. Kotte, Wietse S.C. Eppinga, Martijn Intven, Bas W. Raaymakers, Ina M. Jürgenliemk-Schulz   +13 more
doaj   +1 more source

Feasibility of cardiac-synchronized quantitative T1 and T2 mapping on a hybrid 1.5 Tesla magnetic resonance imaging and linear accelerator system

Physics and Imaging in Radiation Oncology, 2022
Background and Purpose: The heart is important in radiotherapy either as target or organ at risk. Quantitative T1 and T2 cardiac magnetic resonance imaging (qMRI) may aid in target definition for cardiac radioablation, and imaging biomarker for ...
Osman Akdag, Stefano Mandija, Astrid L.H.M.W. van Lier, Pim T.S. Borman, Tim Schakel, Eveline Alberts, Oscar van der Heide, Rutger J. Hassink, Joost J.C. Verhoeff, Firdaus A.A. Mohamed Hoesein, Bas W. Raaymakers, Martin F. Fast   +11 more
doaj   +1 more source

Clinical implementation and feasibility of long-course fractionated MR-guided chemoradiotherapy for patients with esophageal cancer: An R-IDEAL stage 1b/2a evaluation of technical innovation

Clinical and Translational Radiation Oncology, 2022
Purpose: This R-Ideal stage 1b/2a study describes the workflow and feasibility of long-course fractionated online adaptive MR-guided chemoradiotherapy with reduced CTV-to-PTV margins on the 1.5T MR-Linac for patients with esophageal cancer.
M.R. Boekhoff, R. Bouwmans, P.A.H. Doornaert, M.P.W. Intven, J.J.W. Lagendijk, A.L.H.M.W. van Lier, M.J.A. Rasing, S. van de Ven, G.J. Meijer, S. Mook   +9 more
doaj   +1 more source

Automatic 3D Monte-Carlo-based secondary dose calculation for online verification of 1.5 T magnetic resonance imaging guided radiotherapy

Physics and Imaging in Radiation Oncology, 2021
Background and purpose: Hybrid magnetic resonance linear accelerator (MR-Linac) systems represent a novel technology for online adaptive radiotherapy.
Marcel Nachbar, David Mönnich, Oliver Dohm, Melissa Friedlein, Daniel Zips, Daniela Thorwarth   +5 more
doaj   +1 more source

The MOMENTUM Study: An International Registry for the Evidence-Based Introduction of MR-Guided Adaptive Therapy

Frontiers in Oncology, 2020
Purpose: MR-guided Radiation Therapy (MRgRT) allows for high-precision radiotherapy under real-time MR visualization. This enables margin reduction and subsequent dose escalation which may lead to higher tumor control and less toxicity.
Sophie R. de Mol van Otterloo, John P. Christodouleas, Erwin L. A. Blezer, Hafid Akhiat, Kevin Brown, Ananya Choudhury, Dave Eggert, Beth A. Erickson, Corinne Faivre-Finn, Clifton D. Fuller, Joel Goldwein, Shaista Hafeez, Emma Hall, Kevin J. Harrington, Uulke A. van der Heide, Robert A. Huddart, Martijn P. W. Intven, Anna M. Kirby, Susan Lalondrelle, Claire McCann, Bruce D. Minsky, Stella Mook, Marlies E. Nowee, Uwe Oelfke, Kristina Orrling, Arjun Sahgal, Jeffrey G. Sarmiento, Christopher J. Schultz, Robbert J. H. A. Tersteeg, Rob H. N. Tijssen, Alison C. Tree, Baukelien van Triest, William A. Hall, Helena M. Verkooijen   +33 more
doaj   +1 more source