Results 221 to 230 of about 29,252 (289)

Murine Progeria Model Exhibits Delayed Fracture Healing With Senescent Phenotype and Dysregulated Immune Response

open access: yesJournal of Orthopaedic Research, Volume 44, Issue 4, April 2026.
Graphical Abstract This study explores whether a murine model of progeria has a delayed fracture healing phenotype that resembles chronological aging but with an accelerated timeline that could make it a valuable research tool. ABSTRACT An estimated 189 million bone fractures occurred in 2019 making it one of the most globally prevalent injuries ...
Victoria R. Duke   +17 more
wiley   +1 more source

Bacillus cereus Induces Necroptosis in Microglia via the RIPK1/3‐MLKL Pathway

open access: yesMicrobiologyOpen, Volume 15, Issue 2, April 2026.
Bacillus cereus induces necroptosis in murine/human microglia via the RIPK1/3‐MLKL pathway, triggering inflammatory cytokine release—uncovering a new pathogenic mechanism for its severe ocular infection. ABSTRACT Bacillus cereus endophthalmitis is a rapidly progressing intraocular infection that often results in poor visual outcomes due to extensive ...
Jing Yang   +7 more
wiley   +1 more source

Optimized user-guided motion control of modular robots. [PDF]

open access: yesNat Commun
Bolotnikova A   +5 more
europepmc   +1 more source

Therapeutic Galectin‐3 Apheresis Improves Sepsis Outcomes Through Coordinated Neutrophil Modulation and Endothelial Barrier Preservation: A Translational Study

open access: yesMedComm, Volume 7, Issue 4, April 2026.
Gal‐3 apheresis reduces neutrophil hyperactivation (CXCL2/CXCL8, MPO, NETs), preserves endothelial barrier function (tight junctions, vWF/VCAM‐1/ICAM‐1), and attenuates PI3K/AKT/HIF‐1α signaling. These coordinated effects significantly improve hemodynamics, reduce pulmonary edema (ELWI), lower vasopressor and fluid requirements, and increase survival ...
Zhongyi Sun   +7 more
wiley   +1 more source

Meta-frequency modulation in LQR vibration control with chirp excitation. [PDF]

open access: yesSci Rep
Mesbahi S   +5 more
europepmc   +1 more source

Increasing Infusion Times of Hyperpolarized [1‐13C]Pyruvate in a Mouse Brain Maintain Lactate Generation and Approach Pseudo‐Steady State Metabolism

open access: yesMagnetic Resonance in Medicine, Volume 95, Issue 4, Page 2254-2265, April 2026.
ABSTRACT Purpose To investigate whether varying delivery times of hyperpolarized [1‐13C]pyruvate, enabled by the increased apparent T1 dissolved in deuterium oxide (D2O), affects the observed kinetics of glycolytic brain metabolism in vivo. Methods Eighteen healthy mice were injected with 300 μL of hyperpolarized [1‐13C]pyruvate dissolved in D2O at ...
Paola Porcari   +5 more
wiley   +1 more source

Haptic interaction with a human partner for ankle training in chronic stroke: a pilot study. [PDF]

open access: yesJ Neuroeng Rehabil
Short MR   +5 more
europepmc   +1 more source

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