Results 51 to 60 of about 220,281 (307)

Optimal Location of the MR Fluid Segments in the Partially Treated Magnetorheological Fluid Sandwich Beam [PDF]

, 2010
A design optimization methodology is presented to maximize the modal damping factor of a partially treated MR sandwich beam. Modal strain energy approach has been implemented in the finite element model developed for a partially treated MR sandwich beam ...
Vasudevan Rajamohan, Subhash Rakheja, Ramin Sedaghati   +2 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Loss of aquaporin-4 results in glymphatic system dysfunction via brain-wide interstitial fluid stagnation

eLife, 2023
The glymphatic system is a fluid transport network of cerebrospinal fluid (CSF) entering the brain along arterial perivascular spaces, exchanging with interstitial fluid (ISF), ultimately establishing directional clearance of interstitial solutes.
Ryszard Stefan Gomolka, Lauren M Hablitz, Humberto Mestre, Michael Giannetto, Ting Du, Natalie Linea Hauglund, Lulu Xie, Weiguo Peng, Paula Melero Martinez, Maiken Nedergaard, Yuki Mori   +10 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Study on wear of material in contact with MR fluid [PDF]

, 2021
This paper is focused on MR dampers and its critical parts in term of damper`s durability, which seems to be a piston-rod seals, and it should find an ideal material combination of seal and MR fluid for increasing the damper`s life.
Žáček, Jiří
core  

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Using Mason number to predict MR damper performance from limited test data

AIP Advances, 2017
The Mason number can be used to produce a single master curve which relates MR fluid stress versus strain rate behavior across a wide range of shear rates, temperatures, and applied magnetic fields.
Andrew C. Becnel, Norman M. Wereley
doaj   +1 more source

Modelling and design of a dual channel magnetorheological damper [PDF]

, 2013
© Cranfield UniversityA limitation with the current analytical models for predicting the performance of a magnetorheological (MR) damper is that they fail to capture the hysteretic variation of force versus velocity variation correctly.
Bhatnagar, R.
core  

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Rheological Characterization and Performance Evaluation of Magnetorheological Finishing Fluid

Journal of Applied Fluid Mechanics, 2020
The novel controllable behaviour of magnetorheological (MR) fluid is the backbone of magnetorheological fluid-based finishing processes. MR fluid-based finishing processes facilitate better control over finishing forces as the stiffness of MR finishing ...
V. Kumar, R. Kumar, H. Kumar
doaj