Computational and Systems Oncology, Volume 6, Issue 1, December 2026.ABSTRACT Resistance to chemotherapy, which is demonstrated in almost every patient with advanced‐stage lung cancer (ALC), underscores an urgent need to unravel the underlying molecular mechanisms and identify novel strategies to overcome drug resistance. In the present study, an attempt was made to identify epigenetic targets and modulators that can be
Okibur Rahman +2 more
wiley +1 more source
Comparing the Long-Term Effectiveness of Sodium-Glucose Cotransporter 2 Inhibitors Versus Mineralocorticoid Receptor Antagonists as Add-On Therapies in the Management of Heart Failure: A Systematic Review. [PDF]
CureusGeorge V +5 more
europepmc +1 more source
Advances in large DNA fragment assembly for microbial cell factory engineering
Quantitative Biology, Volume 14, Issue 3, September 2026.Abstract The efficient, rapid, and reliable assembly of DNA fragments is essential for advancing metabolic engineering and synthetic biology. With the rapid advancement of DNA synthesis and assembly technologies, the scale of DNA assembly has expanded from single genes to metabolic pathways and even genomes.
Yu Zhang +5 more
wiley +1 more source
A 2025 Literature Review on Arrhythmias: Returning the Focus to Basic Science. [PDF]
J Innov Card Rhythm ManagBushmen S, Collins E, Kiser AC.
europepmc +1 more source
Clinical Pharmacology &Therapeutics, Volume 119, Issue 6, Page 1547-1554, June 2026.Proprotein convertase subtilisin/kexin type 9 (PCSK9) monoclonal antibodies (mAbs) lower LDL cholesterol and may influence cancer through immunomodulatory pathways. However, their effect on human cancer incidence remains unknown. We conducted a retrospective, propensity score‐matched study (Clalit Health Services, Israel, 2010–2023) comparing PCSK9 ...
Inbar Nardi Agmon +10 more
wiley +1 more source
SCOPE-MRI: Bankart Lesion Detection as a Case Study in Data Curation and Deep Learning for Challenging Diagnoses. [PDF]
NPJ Artif IntellSethi S +6 more
europepmc +1 more source
Journal of Arrhythmia, Volume 42, Issue 3, June 2026.After pulsed field ablation with pulmonary vein and posterior wall isolation, a patient developed ischemic stroke due to left carotid artery occlusion. Pathology of the retrieved thrombus revealed an acute red thrombus, suggesting left atrial stunning–induced thrombus formation.
Akinori Matsushima +4 more
wiley +1 more source
Comparative safety profiles of spironolactone, eplerenone, and finerenone: a pharmacovigilance study based on FAERS data from 2004 to 2024. [PDF]
Front PharmacolJi K +8 more
europepmc +1 more source
Respiratory Motion‐Corrected Model‐Based 3D Water‐Fat MRA of the Thorax at 0.55 T
Magnetic Resonance in Medicine, Volume 95, Issue 6, Page 3241-3252, June 2026.ABSTRACT Purpose The goal of this study was to develop a 5‐min 3D MRA acquisition at 0.55 T with predictable scan time, 100% data efficiency, and robust water‐fat separation. Methods For full data efficiency, the proposed method combined self‐gating with retrospective motion correction while ensuring a predictable 5‐min scan time.
Robert Stoll +5 more
wiley +1 more source
Primary aldosteronism: pharmacotherapy <i>vs</i> surgery <i>vs</i> embolization efficacy - systematic review and network meta-analysis of studies predominantly conducted in China. [PDF]
Front Endocrinol (Lausanne)Li G, Xu W, Li C, Hu P, Qin S.
europepmc +1 more source