The Effect of Mineralocorticoid Receptor Antagonists on Heart Failure with Nonreduced Ejection Fraction: A Systematic Review and Meta-Analysis. [PDF]
De Luca C +10 more
europepmc +1 more source
ABSTRACT RASopathies are clinically overlapping neurodevelopmental syndromes resulting from germline mutations in genes involved in the rat sarcoma/mitogen‐activated protein kinases (RAS/MAPK) pathway. Historically, RASopathies have been described by clinical phenotypes, such as Noonan syndrome and Neurofibromatosis type I.
Anastasia‐Vasiliki Madenidou +6 more
wiley +1 more source
Does Guideline-Directed Medical Therapy Reduce the Incidence of Ventricular Arrhythmias in Patients With HFrEF? [PDF]
Nomoto Y, Kataoka N, Imamura T.
europepmc +1 more source
ABSTRACT Physicians evaluating pediatric movement disorders, especially chorea, should consider a broad differential diagnosis, including vascular etiologies such as moyamoya disease. Prompt recognition, appropriate neuroimaging, and early diagnosis are crucial for guiding management and optimizing patient outcomes.
Lina Okar +4 more
wiley +1 more source
Effect of different diastolic blood pressure levels on the prognosis of patients with heart failure after acute myocardial infarction. [PDF]
Sun X +9 more
europepmc +1 more source
ABSTRACT X‐linked adrenoleukodystrophy (X‐ALD) is a genetic peroxisome disorder linked to ABCD1 mutation, characterized by rapid and complex clinical symptoms. We here report a case of X‐ALD manifesting solely as dysarthria, associated with an undefined mutation in the ABCD1 gene, underscoring the necessity of atypical clinical symptoms in X‐ALD ...
Fu‐Qing Zhang +4 more
wiley +1 more source
Mineralocorticoid receptor antagonists for acute myocardial infarction: a systematic review and meta-analysis of randomised controlled trials. [PDF]
Ang SP +7 more
europepmc +1 more source
Large Symptomatic Splenic Pseudocyst: Case Report of a Rare Entity
ABSTRACT Large symptomatic splenic pseudocysts, though rare, should be considered in patients with persistent left upper abdominal pain as we report in our case. Imaging enables diagnosis, and laparoscopic spleen‐preserving cyst decompression and deroofing provide a safe, effective treatment, relieving symptoms while maintaining splenic function and ...
Tasnuva Habib Neha +3 more
wiley +1 more source
Bridging heart failure clinic-based guideline-directed medical therapy optimization and real-world practice in heart failure with reduced ejection fraction (HFrEF). [PDF]
Sen T, Demir M, Batak CN.
europepmc +1 more source
Elevated admission GDF‐15 levels are associated with increased mortality in acute heart failure. This meta‐analysis of 10 studies (N = 3724) found a pooled RR of 2.82 (95% CI: 2.39–3.32; p < 0.001; I² = 0%), supporting GDF‐15 as a promising biomarker for early risk stratification in AHF patients.
Pingkui Jin +5 more
wiley +1 more source

