Advances in large DNA fragment assembly for microbial cell factory engineering
Abstract The efficient, rapid, and reliable assembly of DNA fragments is essential for advancing metabolic engineering and synthetic biology. With the rapid advancement of DNA synthesis and assembly technologies, the scale of DNA assembly has expanded from single genes to metabolic pathways and even genomes.
Yu Zhang +5 more
wiley +1 more source
Proprotein convertase subtilisin/kexin type 9 (PCSK9) monoclonal antibodies (mAbs) lower LDL cholesterol and may influence cancer through immunomodulatory pathways. However, their effect on human cancer incidence remains unknown. We conducted a retrospective, propensity score‐matched study (Clalit Health Services, Israel, 2010–2023) comparing PCSK9 ...
Inbar Nardi Agmon +10 more
wiley +1 more source
Assessment of 10CrMo9-10 Power Engineering Steel Degradation State by Using Small Punch Test. [PDF]
Majchrowicz K +7 more
europepmc +1 more source
After pulsed field ablation with pulmonary vein and posterior wall isolation, a patient developed ischemic stroke due to left carotid artery occlusion. Pathology of the retrieved thrombus revealed an acute red thrombus, suggesting left atrial stunning–induced thrombus formation.
Akinori Matsushima +4 more
wiley +1 more source
Fast sensorless collision detection for resource-constrained pmsm controllers using an FFRLS-based method. [PDF]
Zhao D, Ren T, Huang G, Liu M.
europepmc +1 more source
The Use of Pointwise Encoding Time Reduction With Radial Acquisition MRA to Assess Middle Cerebral Artery Stenosis Pre- and Post-stent Angioplasty: Comparison With 3D Time-of-Flight MRA and DSA. [PDF]
Zhang F +12 more
europepmc +1 more source
Respiratory Motion‐Corrected Model‐Based 3D Water‐Fat MRA of the Thorax at 0.55 T
ABSTRACT Purpose The goal of this study was to develop a 5‐min 3D MRA acquisition at 0.55 T with predictable scan time, 100% data efficiency, and robust water‐fat separation. Methods For full data efficiency, the proposed method combined self‐gating with retrospective motion correction while ensuring a predictable 5‐min scan time.
Robert Stoll +5 more
wiley +1 more source
The Effects of Aldosterone on Hypertension-Associated Kidney Injury in a Tg-hAS Mouse Model. [PDF]
Gu H, Chen Z, Du N, Yang S, Yu Y, Du Y.
europepmc +1 more source
Taboos as Drivers for Counterculture: Normalizing Misogyny in Incel Communities and Beyond
Journal of Social Philosophy, EarlyView.
Mihaela Popa‐Wyatt, Justina Berškytė
wiley +1 more source
Context‐Dependent Temporal Changes in Hypnotics Involved in Suicide Attempts
Temporal changes in hypnotics involved in suicide attempts showed context‐dependent shifts. Dual orexin receptor antagonists increased significantly, while benzodiazepine involvement declined only in overdose‐related attempts. Melatonin receptor agonists showed no significant trend during 2020.
Taro Sasaki +5 more
wiley +1 more source

