Results 131 to 140 of about 109,024 (284)
Comparative study between ultrasound and MR enterography in evaluation of Crohn’s disease
Background Crohn’s disease is a chronic inflammatory bowel disease that can affect any part of the gut. Endoscopy is the gold standard for diagnosis, but it only assesses mucosal lesions.
Nada Sayed Mahdy +5 more
doaj +1 more source
Exploring fundus‐controlled mesopic and scotopic perimetry in inherited retinal disease
Abstract Purpose Microperimetry is increasingly used as an outcome measure in clinical trials for retinal disease. This study compares mesopic and scotopic microperimetry in a heterogeneous cohort of patients with inherited retinal disease to assess their suitability as clinical trial outcome measures and to determine the most appropriate testing ...
Laura J. Taylor +4 more
wiley +1 more source
Abstract Background Attention‐deficit/hyperactivity disorder (ADHD) is highly prevalent in adults with anxiety and related disorders (ARDs). Quantitative research on this clinical population is mixed, with some studies suggesting that anxiety is protective against some symptoms of ADHD and others in which co‐occurring ARDs and ADHD are linked to poorer
Arij Alarachi +3 more
wiley +1 more source
Soft MRE Gripper: Preliminary Study
Soft robotics focuses on the imitation of the work of living organisms and mostly utilizes soft deformable materials for actuation or object manipulation tasks. Soft robots or grippers can be used for tasks which are beyond the reach of conventional rigid body ones.
Denys Gutenko +3 more
openaire +1 more source
Abstract Background Generalized anxiety disorder during the perinatal period (pGAD) is highly prevalent and associated with adverse outcomes for both mother/birthing person (BP) and child. Yet, most treatment studies rely on researcher‐selected outcomes that may not reflect patient priorities.
Emma M. Stallwood +6 more
wiley +1 more source
ABSTRACT Aims Metabolic dysfunction‐associated steatohepatitis (MASH) is a leading cause of cirrhosis. NIS2+ is a recently approved serum‐based test combining two biomarkers (miR‐34a‐5p and YKL‐40) to identify at‐risk MASH (i.e., MASH and significant fibrosis). Objective To assess the prevalence of at‐risk MASH by NIS2+ in individuals from primary care
Srilaxmi Kalavalapalli +12 more
wiley +1 more source
Congenital dyserythropoietic anemia type I (CDA‐I) arises from mutations in Codanin1 and CDIN1. Using quantitative biophysical approaches, we show that disease‐associated mutations disrupt the CDIN1‐Codanin1 complex. Our findings provide critical insights into the molecular mechanism that links protein dysfunction to disturbing chromatin arrangement ...
Martin Stojaspal +8 more
wiley +1 more source
Investigated mutations in transthyretin (TTR) disrupt the F87‐centered hydrophobic core that stabilizes its tetrameric structure. The mild I107V mutation weakens inter‐chain packing, while H88R fully abolishes tetramer formation, yielding a monomeric, aggregation‐prone form. Structural, biophysical, and computational analyses reveal that both mutations
István L. Bódy +7 more
wiley +1 more source
Two‐dimensional shear wave elastography demonstrated strong correlation with magnetic resonance elastography and high diagnostic accuracy for liver fibrosis across stages in 744 patients with chronic liver disease, supporting its role as a reliable non‐invasive tool for fibrosis assessment.
Takashi Nishimura +26 more
wiley +1 more source

