Results 131 to 140 of about 109,024 (284)

Comparative study between ultrasound and MR enterography in evaluation of Crohn’s disease

open access: yesThe Egyptian Journal of Radiology and Nuclear Medicine
Background Crohn’s disease is a chronic inflammatory bowel disease that can affect any part of the gut. Endoscopy is the gold standard for diagnosis, but it only assesses mucosal lesions.
Nada Sayed Mahdy   +5 more
doaj   +1 more source

Exploring fundus‐controlled mesopic and scotopic perimetry in inherited retinal disease

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose Microperimetry is increasingly used as an outcome measure in clinical trials for retinal disease. This study compares mesopic and scotopic microperimetry in a heterogeneous cohort of patients with inherited retinal disease to assess their suitability as clinical trial outcome measures and to determine the most appropriate testing ...
Laura J. Taylor   +4 more
wiley   +1 more source

A qualitative investigation of the lived experiences of adults with anxiety and related disorders and ADHD: Interconnectedness of symptoms and implications for improving care

open access: yesBritish Journal of Clinical Psychology, EarlyView.
Abstract Background Attention‐deficit/hyperactivity disorder (ADHD) is highly prevalent in adults with anxiety and related disorders (ARDs). Quantitative research on this clinical population is mixed, with some studies suggesting that anxiety is protective against some symptoms of ADHD and others in which co‐occurring ARDs and ADHD are linked to poorer
Arij Alarachi   +3 more
wiley   +1 more source

Soft MRE Gripper: Preliminary Study

open access: yes
Soft robotics focuses on the imitation of the work of living organisms and mostly utilizes soft deformable materials for actuation or object manipulation tasks. Soft robots or grippers can be used for tasks which are beyond the reach of conventional rigid body ones.
Denys Gutenko   +3 more
openaire   +1 more source

Developing a core outcome set for generalized anxiety disorder during the perinatal period: Identifying core treatment outcomes in perinatal anxiety

open access: yesBritish Journal of Clinical Psychology, EarlyView.
Abstract Background Generalized anxiety disorder during the perinatal period (pGAD) is highly prevalent and associated with adverse outcomes for both mother/birthing person (BP) and child. Yet, most treatment studies rely on researcher‐selected outcomes that may not reflect patient priorities.
Emma M. Stallwood   +6 more
wiley   +1 more source

High Prevalence of Metabolic Dysfunction–Associated Steatohepatitis With Significant Fibrosis in Primary Care and Endocrinology Clinics

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Metabolic dysfunction‐associated steatohepatitis (MASH) is a leading cause of cirrhosis. NIS2+ is a recently approved serum‐based test combining two biomarkers (miR‐34a‐5p and YKL‐40) to identify at‐risk MASH (i.e., MASH and significant fibrosis). Objective To assess the prevalence of at‐risk MASH by NIS2+ in individuals from primary care
Srilaxmi Kalavalapalli   +12 more
wiley   +1 more source

Anemia‐associated mutations disrupt the CDIN1‐Codanin1 complex in inherited congenital dyserythropoietic anemia I (CDA‐I) disease

open access: yesThe FEBS Journal, EarlyView.
Congenital dyserythropoietic anemia type I (CDA‐I) arises from mutations in Codanin1 and CDIN1. Using quantitative biophysical approaches, we show that disease‐associated mutations disrupt the CDIN1‐Codanin1 complex. Our findings provide critical insights into the molecular mechanism that links protein dysfunction to disturbing chromatin arrangement ...
Martin Stojaspal   +8 more
wiley   +1 more source

A theoretical approach to local attenuation measurements of shear waves by MRE. Preliminary experimental results

open access: yesOpen Physics, 2005
Klinkosz Tomasz   +3 more
doaj   +1 more source

Investigating transthyretin variants H88R and I107V in amyloid priming: From destabilization to complete dissociation

open access: yesThe FEBS Journal, EarlyView.
Investigated mutations in transthyretin (TTR) disrupt the F87‐centered hydrophobic core that stabilizes its tetrameric structure. The mild I107V mutation weakens inter‐chain packing, while H88R fully abolishes tetramer formation, yielding a monomeric, aggregation‐prone form. Structural, biophysical, and computational analyses reveal that both mutations
István L. Bódy   +7 more
wiley   +1 more source

Diagnostic Impact of Two‐Dimensional Shear Wave Elastography for Liver Fibrosis: A Multicenter Retrospective Study

open access: yesHepatology Research, EarlyView.
Two‐dimensional shear wave elastography demonstrated strong correlation with magnetic resonance elastography and high diagnostic accuracy for liver fibrosis across stages in 744 patients with chronic liver disease, supporting its role as a reliable non‐invasive tool for fibrosis assessment.
Takashi Nishimura   +26 more
wiley   +1 more source

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