Results 151 to 160 of about 29,884 (295)

Developing a core outcome set for generalized anxiety disorder during the perinatal period: Identifying core treatment outcomes in perinatal anxiety

open access: yesBritish Journal of Clinical Psychology, EarlyView.
Abstract Background Generalized anxiety disorder during the perinatal period (pGAD) is highly prevalent and associated with adverse outcomes for both mother/birthing person (BP) and child. Yet, most treatment studies rely on researcher‐selected outcomes that may not reflect patient priorities.
Emma M. Stallwood   +6 more
wiley   +1 more source

Comparative effectiveness of chimeric antigen receptor (CAR) T‐cell therapy versus historical controls in patients with relapse/refractory aggressive B‐cell lymphoma: An indirect treatment comparison in the real‐world setting

open access: yesBritish Journal of Haematology, EarlyView.
Summary Single‐arm studies demonstrate dramatic improvements in survival in patients with relapsed/refractory (R/R) aggressive B‐cell lymphomas but with significant toxicities and at exceptionally high costs. The objective of this study was to evaluate the real‐world health outcomes of aggressive B‐cell lymphoma patients treated with publicly funded ...
Pierre J. A. Villeneuve   +17 more
wiley   +1 more source

Comparative study between ultrasound and MR enterography in evaluation of Crohn’s disease

open access: yesThe Egyptian Journal of Radiology and Nuclear Medicine
Background Crohn’s disease is a chronic inflammatory bowel disease that can affect any part of the gut. Endoscopy is the gold standard for diagnosis, but it only assesses mucosal lesions.
Nada Sayed Mahdy   +5 more
doaj   +1 more source

Anemia‐associated mutations disrupt the CDIN1‐Codanin1 complex in inherited congenital dyserythropoietic anemia I (CDA‐I) disease

open access: yesThe FEBS Journal, EarlyView.
Congenital dyserythropoietic anemia type I (CDA‐I) arises from mutations in Codanin1 and CDIN1. Using quantitative biophysical approaches, we show that disease‐associated mutations disrupt the CDIN1‐Codanin1 complex. Our findings provide critical insights into the molecular mechanism that links protein dysfunction to disturbing chromatin arrangement ...
Martin Stojaspal   +8 more
wiley   +1 more source

Synchronous Measuring Techniques in Parallel to MRE: Study of Pressure, Pre-Tension, and Surface Dynamics [PDF]

open access: yes, 2016
The contents of this dissertation include investigations in Magnetic Resonance Elastography (MRE) using a preclinical 9.4 Tesla small animal Magnetic Resonance Imaging (MRI) system along with synthetic materials that mimic the mechanical properties of ...
Spencer T. Brinker (7987901)
core  

Investigating transthyretin variants H88R and I107V in amyloid priming: From destabilization to complete dissociation

open access: yesThe FEBS Journal, EarlyView.
Investigated mutations in transthyretin (TTR) disrupt the F87‐centered hydrophobic core that stabilizes its tetrameric structure. The mild I107V mutation weakens inter‐chain packing, while H88R fully abolishes tetramer formation, yielding a monomeric, aggregation‐prone form. Structural, biophysical, and computational analyses reveal that both mutations
István L. Bódy   +7 more
wiley   +1 more source

Enhancing Recharge in the Edwards Aquifer, Texas: Measures, Outcomes, and Lessons for Karst Aquifers

open access: yesGroundwater, EarlyView.
Abstract Managed aquifer recharge is a widely adopted method that involves storing excess water underground for future use. While managed aquifer recharge has been applied globally to different aquifer types, its use in karst aquifers is less common due to the unique hydrogeological characteristics of these systems, including high permeability ...
Neelam Thapa Magar, Robert E. Mace
wiley   +1 more source

Diagnostic Impact of Two‐Dimensional Shear Wave Elastography for Liver Fibrosis: A Multicenter Retrospective Study

open access: yesHepatology Research, EarlyView.
Two‐dimensional shear wave elastography demonstrated strong correlation with magnetic resonance elastography and high diagnostic accuracy for liver fibrosis across stages in 744 patients with chronic liver disease, supporting its role as a reliable non‐invasive tool for fibrosis assessment.
Takashi Nishimura   +26 more
wiley   +1 more source

Prevalence of cardiometabolic diseases among ART‐naïve people with HIV: A global systematic review and meta‐analysis

open access: yesHIV Medicine, EarlyView.
Abstract Introduction The burden of cardiometabolic diseases (CMDs) is rising in people with HIV (PWH). While extensive data exist on CMD prevalence in PWH receiving antiretroviral therapy (ART), comprehensive data on ART‐naïve PWH are scarce. We aimed to estimate the global prevalence of hypertension, diabetes, obesity and dyslipidaemia among ART ...
Peter Vanes Ebasone   +5 more
wiley   +1 more source

A theoretical approach to local attenuation measurements of shear waves by MRE. Preliminary experimental results

open access: yesOpen Physics, 2005
Klinkosz Tomasz   +3 more
doaj   +1 more source

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