Results 31 to 40 of about 1,090,723 (249)

Altered Functional Connectivity of Insular Subregions in Type 2 Diabetes Mellitus

Frontiers in Neuroscience, 2021
Diabetes-related brain damage can lead to cognitive decline and increase the risk of depression, but the neuropathological mechanism of this phenomenon remains unclear.
Dongsheng Zhang, Man Wang, Jie Gao, Yang Huang, Fei Qi, Yumeng Lei, Kai Ai, Xuejiao Yan, Miao Cheng, Yu Su, Xiaoyan Lei, Xiaoling Zhang   +11 more
doaj   +1 more source

A Comparative Study of Cerebral Oxygenation During Exercise in Hemodialysis and Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou, Konstantina Dipla, Danai Faitatzidou, Fotini Iatridi, Areti Georgiou, Artemios Karagiannidis, Erasmia Sampani, Chrysostomos Dimitriadis, Aggelos Koutlas, Andreas Zafeiridis, Pantelis Sarafidis   +10 more
wiley   +1 more source

Combination of PI-RADS version 2.1 and amide proton transfer values for the detection of clinically significant prostate cancer

BMC Cancer
Background The goal of this study was to assess whether combining amide proton transfer (APT)-weighted MRI with the Prostate Imaging Reporting and Data System scoring system version 2.1 (PI-RADS V2.1) could increase diagnostic accuracy compared to PI ...
Li Zhang, Longchao Li, Xia Zhe, Min Tang, Xiaoyan Lei, Jing Zhang, Xianglong Duan   +6 more
doaj   +1 more source

Altered cortical thickness-based structural covariance networks in type 2 diabetes mellitus

Frontiers in Neuroscience
Cognitive impairment is a common complication of type 2 diabetes mellitus (T2DM), and early cognitive dysfunction may be associated with abnormal changes in the cerebral cortex.
Yang Huang, Xin Zhang, Miao Cheng, Zhen Yang, Wanting Liu, Kai Ai, Min Tang, Xiaoling Zhang, Xiaoyan Lei, Dongsheng Zhang   +9 more
doaj   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

Characterization of changes in the resting-state intrinsic network in patients with diabetic peripheral neuropathy

Scientific Reports
Diabetic peripheral neuropathy (DPN) is the most common complication of type 2 diabetes mellitus (T2DM) and is often accompanied by a variety of cognitive and emotional deficits, but the neurologic mechanisms underlying these deficits have not been fully
Dongsheng Zhang, Yang Huang, Yitong Guan, Xiaoling Zhang, Peichun Pan, Xuejiao Yan, Xiaoyan Lei, Min Tang, Kai Ai, Jie Gao   +9 more
doaj   +1 more source

Automatic linear measurements of the fetal brain on MRI with deep neural networks [PDF]

, 2021
Netanell Avisdris, Bossmat Yehuda, Ori Ben-Zvi, Daphna Link‐Sourani, Liat Ben‐Sira, Elka Miller, Elena Zharkov, Dafna Ben Bashat, Leo Joskowicz   +8 more
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Endometriosis and Its Myriad Presentations: Magnetic Resonance Imaging-Based Pictorial Review

Indian Journal of Radiology and Imaging, 2021
Endometriosis is a major cause of infertility and pain in females in the reproductive age group. It is a result of ectopic functional endometrial cells outside the uterus. It consists of a spectrum of findings from superficial to deep implants initiating
Seema Sud, Tarvinder Bir Singh Buxi, Swapnil Sheth, Samarjit Singh Ghuman   +3 more
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source