Results 51 to 60 of about 1,380,546 (262)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Characterization of changes in the resting-state intrinsic network in patients with diabetic peripheral neuropathy

Scientific Reports
Diabetic peripheral neuropathy (DPN) is the most common complication of type 2 diabetes mellitus (T2DM) and is often accompanied by a variety of cognitive and emotional deficits, but the neurologic mechanisms underlying these deficits have not been fully
Dongsheng Zhang, Yang Huang, Yitong Guan, Xiaoling Zhang, Peichun Pan, Xuejiao Yan, Xiaoyan Lei, Min Tang, Kai Ai, Jie Gao   +9 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

MRI

, 2018
    MRI made on 2017-08-14 at the Instituto de Neurobiología UNAM Querétaro in Mexico to Nathalie Regard b.
Regard Nathalie (5583737)
core   +1 more source

Altered cortical thickness-based structural covariance networks in type 2 diabetes mellitus

Frontiers in Neuroscience
Cognitive impairment is a common complication of type 2 diabetes mellitus (T2DM), and early cognitive dysfunction may be associated with abnormal changes in the cerebral cortex.
Yang Huang, Xin Zhang, Miao Cheng, Zhen Yang, Wanting Liu, Kai Ai, Min Tang, Xiaoling Zhang, Xiaoyan Lei, Dongsheng Zhang   +9 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Combination of PI-RADS version 2.1 and amide proton transfer values for the detection of clinically significant prostate cancer

BMC Cancer
Background The goal of this study was to assess whether combining amide proton transfer (APT)-weighted MRI with the Prostate Imaging Reporting and Data System scoring system version 2.1 (PI-RADS V2.1) could increase diagnostic accuracy compared to PI ...
Li Zhang, Longchao Li, Xia Zhe, Min Tang, Xiaoyan Lei, Jing Zhang, Xianglong Duan   +6 more
doaj   +1 more source

Comparison of Different Machine Models Based on Contrast-Enhanced Computed Tomography Radiomic Features to Differentiate High From Low Grade Clear Cell Renal Cell Carcinomas

Frontiers in Oncology, 2021
PurposeThis study was to investigate the role of different radiomics models with enhanced computed tomography (CT) scan in differentiating low from high grade renal clear cell carcinomas.Materials and MethodsCT data of 190 cases with pathologically ...
Xu Pei, Ping Wang, Jia-Liang Ren, Xiao-Ping Yin, Xiao-Ping Yin, Lu-Yao Ma, Yun Wang, Xi Ma, Bu-Lang Gao   +8 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Characterizing aging in the human brainstem using quantitative multimodal MRI analysis [PDF]

, 2013
Aging is ubiquitous to the human condition. The MRI correlates of healthy aging have been extensively investigated using a range of modalities, including volumetric MRI, quantitative MRI (qMRI), and diffusion tensor imaging.
Stephen M. Fleming, Stephen M Fleming, Frackowiak, R, John eAshburner, Antoine eLutti, Bogdan eDraganski, Frackowiak, R., Ashburner, J, Rumana Chowdhury, Chowdhury, R., Christian Lambert, Draganski, Bogdan, Fitzgerald, TH, Thomas eFitzgerald, Lambert, C., Hutton, C., Chloe Hutton, Lambert, C, Chowdhury, R, Chowdhury, Rumana, Antoine Lutti, Fleming, Stephen M., Fleming, SM, Chloe eHutton, Lutti, Antoine, John Ashburner, Draganski, B, Ashburner, J., Bogdan Draganski, Fitzgerald, Thomas H. B., Rumana eChowdhury, Hutton, Chloe, Richard Frackowiak, Lambert, Christian, Christian eLambert, Thomas H. B. FitzGerald, Fitzgerald, T.H., Lutti, A, Lutti, A., Ashburner, John, Fleming, S.M., Draganski, B., Richard eFrackowiak, Hutton, C, Frackowiak, Richard   +44 more
core   +1 more source