Results 51 to 60 of about 1,793,451 (304)

Differential Renoprotective Actions of Simvastatin and Rosuvastatin in Streptozotocin-Induced Diabetes in Sprague-Dawley Rat

Archives of Pharmaceutical Sciences Ain Shams University, 2020
Diabetic nephropathy (DN) is the most frequent cause of the end-stage renal disease (ESRD) in about 33% of diabetic patients. The present study aimed to explore the renoprotective effects of simvastatin (SV) and rosuvastatin (RSU) on the kidney of ...
Rowaida Refaat, Asmaa Eldeeb, Marwa Bakir, Eman I El-Abd, Emad El-Bassiouni   +4 more
doaj   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Clinical utility of gadobenate dimeglumine in contrast-enhanced MRI of the breast: a review [PDF]

, 2015
Breast magnetic resonance imaging (MRI) is considered the technique with the highest sensitivity for breast cancer detection. Gadobenate dimeglumine is a gadolinium-based contrast agent (GBCA) that is specifically approved in Europe for breast MRI and ...
Kirchin, Miles, Luciani, MARIA LAURA, Pediconi, Federica, Telesca, Marianna   +3 more
core   +1 more source

Synthetic MRI plus FSE-PROPELLER DWI for differentiating malignant from benign head and neck tumors: a preliminary study

Frontiers in Oncology, 2023
BackgroundPreoperative classification of head and neck (HN) tumors remains challenging, especially distinguishing early cancerogenic masses from benign lesions. Synthetic MRI offers a new way for quantitative analysis of tumors.
Baohong Wen, Zanxia Zhang, Jing Zhu, Liang Liu, Zijun Liu, Xiaoyue Ma, Kaiyu Wang, Lizhi Xie, Yong Zhang, Jingliang Cheng   +9 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

A bisphosphonate for F-19-magnetic resonance imaging [PDF]

, 2016
19F-magnetic resonance imaging (MRI) is a promising technique that may allow us to measure the concentration of exogenous fluorinated imaging probes quantitatively in vivo.
Botnar, RM, De Rosales, RTM, Kenny, GD, Shaw, KP, Sivachelvam, S, White, AJP   +5 more
core   +1 more source

Characterization of changes in the resting-state intrinsic network in patients with diabetic peripheral neuropathy

Scientific Reports
Diabetic peripheral neuropathy (DPN) is the most common complication of type 2 diabetes mellitus (T2DM) and is often accompanied by a variety of cognitive and emotional deficits, but the neurologic mechanisms underlying these deficits have not been fully
Dongsheng Zhang, Yang Huang, Yitong Guan, Xiaoling Zhang, Peichun Pan, Xuejiao Yan, Xiaoyan Lei, Min Tang, Kai Ai, Jie Gao   +9 more
doaj   +1 more source

Comparison of Different Machine Models Based on Contrast-Enhanced Computed Tomography Radiomic Features to Differentiate High From Low Grade Clear Cell Renal Cell Carcinomas

Frontiers in Oncology, 2021
PurposeThis study was to investigate the role of different radiomics models with enhanced computed tomography (CT) scan in differentiating low from high grade renal clear cell carcinomas.Materials and MethodsCT data of 190 cases with pathologically ...
Xu Pei, Ping Wang, Jia-Liang Ren, Xiao-Ping Yin, Xiao-Ping Yin, Lu-Yao Ma, Yun Wang, Xi Ma, Bu-Lang Gao   +8 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Combination of PI-RADS version 2.1 and amide proton transfer values for the detection of clinically significant prostate cancer

BMC Cancer
Background The goal of this study was to assess whether combining amide proton transfer (APT)-weighted MRI with the Prostate Imaging Reporting and Data System scoring system version 2.1 (PI-RADS V2.1) could increase diagnostic accuracy compared to PI ...
Li Zhang, Longchao Li, Xia Zhe, Min Tang, Xiaoyan Lei, Jing Zhang, Xianglong Duan   +6 more
doaj   +1 more source