Results 181 to 190 of about 97,528 (241)

A Cascade Recognition of Activatable Probe for Fluorescence Navigation Glioblastoma Surgery: Overcoming Blood‐Brain Barrier and Off‐Target Limitations

Advanced Science, EarlyView.
A cascade recognition of activatable probe ANG‐hCy‐MC is used for high‐precision depiction of glioblastoma (GBM) margin. This probe crosses the blood‐brain barrier (BBB) through LRP1 receptor‐mediated transport and provides excellent fluorescence signal contrast between the tumor and normal tissues, thereby enabling ultra‐selective imaging and precise ...
Xinru An, Yu Guo, Yongning Bian, Yanli Tan, Chuan Fang, Hengzhu Zhang, Xueqian Chen, Lin Yuan, Dongdong Su   +8 more
wiley   +1 more source

A Targeted Multi-Crystalline Manganese Oxide as a Tumor-Selective Nano-Sized MRI Contrast Agent for Early and Accurate Diagnosis of Tumors. [PDF]

Int J Nanomedicine
Yang G, Xia J, Dai X, Zhao H, Gao W, Ding W, Tao X, Zhu L.   +7 more
europepmc   +1 more source

Collagen-targeted MRI contrast agent for liver fibrosis detection. [PDF]

Nat Rev Gastroenterol Hepatol, 2020
Kennedy P, Taouli B.
europepmc   +1 more source

Hepatobiliary MRI contrast agents

, 2013
J. Ballinger, Mohammad Taghi Niknejad, Zhen Chang   +2 more
openaire   +1 more source

PROTAC‑Mediated HMGCR Depletion Reprograms Lipid Metabolism in Breast Cancer to Potentiate Photoimmunotherapy via Ferroptosis

Advanced Science, EarlyView.
This work introduces a study that identifies HMGCR as a novel target in TNBC and develops a light‐gated PROTAC nanomedicine. Upon irradiation, this agent selectively degrades HMGCR, reprogramming lipid metabolism to induce ferroptosis and potent antitumor immunity, thereby significantly enhancing photoimmunotherapy efficacy.
Tong Su, Guang Li, Yudong Guan, Qi Tian, Youzhi Qi, Yanqiu Zhang, Wenqian Wei, Xinxin Duan, Jiaxin Rui, Hongyan Zhu, Zengping Lin, Changchuan Xie, Zheni Xu, Yaying Wu, Xin Peng, Zhenjie Wang, Kun Chen, Xiaoyan Xin, Bing Zhang   +18 more
wiley   +1 more source

MRI contrast agent safety

, 2013
J. Ballinger, Rohit Sharma, Arlene Campos   +2 more
openaire   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Intravenous MRI contrast agents

, 2013
J. Ballinger, Daniel MacManus, Patrick Rock   +2 more
openaire   +1 more source

Fluorinated Hypoxia‐Responsive Aza‐BODIPY for NIR‐II FL/19F MR/PA Imaging and Phototherapy of Lung Cancer

Advanced Science, EarlyView.
Fluorinated N‐oxide aza‐BODIPY nanoemulsions integrate fluorination‐driven molecular design with co‐assembly in fluorinated oil for multimodal imaging‐guided phototherapy. The co‐assembly redshifts fluorescence into the NIR‐II window for deep‐tissue imaging and provides a unified 19F signal for background‐free, quantitative MRI.
Anfeng Li, Fang Wang, Mou Jiang, Yu Li, Xin Zhou, Zhong‐Xing Jiang   +5 more
wiley   +1 more source

Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare

Advanced Science, EarlyView.
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu, Haolin Fan, Minwoo Kim, Tong Zhou, Pinyi Yang, Lingdi Zhao, Yiran Wang, Ziyuan Che, Chia‐Wei Liu, Bingbing Li, Yangzhi Zhu   +10 more
wiley   +1 more source