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Gadolinium as an MRI Contrast Agent
Future Medicinal Chemistry, 2018MRI contrast is often enhanced using a contrast agent. Gd3+-complexes are the most widely used metallic MRI agents, and several types of Gd3+-based contrast agents (GBCAs) have been developed. Furthermore, recent advances in MRI technology have, in part, been driven by the development of new GBCAs.
Hee-Kyung, Kim +2 more
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New designs for MRI contrast agents
Journal of Computer-Aided Molecular Design, 2003New designs for Magnetic Resonance Imaging contrast agents are presented. Essentially, they all are host-guest inclusion complexes between y-cyclodextrins and polyazamacrocycles of gadolinium (III) ion. Substitutions have been made to the host to optimise the host-guest association.
Fernandes, P. A. +21 more
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2000
At the dawn of the magnetic resonance era it was suggested that contrast media would not be necessary because of the enhanced intrinsic tissue contrast already present with MRI. It was even predicted that many specific diagnoses could be made as a result of the individual relaxation times of various disease processes.
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At the dawn of the magnetic resonance era it was suggested that contrast media would not be necessary because of the enhanced intrinsic tissue contrast already present with MRI. It was even predicted that many specific diagnoses could be made as a result of the individual relaxation times of various disease processes.
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Paramagnetic iron (III) MRI contrast agents
Magnetic Resonance in Medicine, 1991AbstractThe advantages and disadvantages of a number of paramagnetic Fe(III)‐containing MRI contrast agents are discussed. © 1991 Academic Press, Inc.
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Nanostructured T1 MRI contrast agents
Journal of Materials Chemistry, 2009Recent advances on new T1 MRI contrast agents using nanostructured materials will be presented. Paramagnetic Gd3+ ions have been immobilized in nanostructured matrices such as liposomes, perfluorocarbons, silica-based nanoparticles, emulsions, and carbon nanotube to generate nanostructured ionic T1 MRI contrast agents with high relaxivity.
Hyon Bin Na, Taeghwan Hyeon
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Topics in Magnetic Resonance Imaging, 2016
Accurate detection of lesions throughout the body is of paramount importance in contrast-enhanced magnetic resonance imaging (MRI). Optimal contrast agent performance is therefore of great importance and given the number of MRI contrast agent options today, this topic is of much ongoing study.
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Accurate detection of lesions throughout the body is of paramount importance in contrast-enhanced magnetic resonance imaging (MRI). Optimal contrast agent performance is therefore of great importance and given the number of MRI contrast agent options today, this topic is of much ongoing study.
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Responsive Paramagnetic MRI Contrast Agents
2003A method is claimed based on CEST procedure for the in vivo or in vitro determination of physical or chemical parameters which includes the use of a responsive paramagnetic CEST contrast agent.
AIME, Silvio +3 more
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Novel pH-Reporter MRI Contrast Agents
Angewandte Chemie International Edition, 2002AIME, Silvio +2 more
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Contrast agents in cardiac MRI
1999In MRI studies, a contrast agent is defined as a substance that, once injected to the patient, modifies selectively the signal intensity of a particular anatomical structure by changing relaxation properties of tissues. Different magnetic substances have been tested, including manganese, gadolinium, dysprosium, and iron oxide, their effects depending ...
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