Results 151 to 160 of about 11,586,854 (252)

FoxO1 Deficiency in Monocytic Myeloid‐Derived Suppressor Cells Exacerbates B Cell Dysfunction in Systemic Lupus Erythematosus

Arthritis &Rheumatology, Volume 77, Issue 4, Page 423-438, April 2025.
Objective Myeloid‐derived suppressor cells (MDSCs) contribute to the pathogenesis of systemic lupus erythematosus (SLE), in part due to promoting the survival of plasma cells. FoxO1 expression in monocytic MDSCs (M‐MDSCs) exhibits a negative correlation with the SLE Disease Activity Index score.
Liping Tan, Wei Kong, Kangxing Zhou, Shuangan Wang, Jun Liang, Yayi Hou, Huan Dou   +6 more
wiley   +1 more source

Jasper and Stella: distillation of SOTA embedding models [PDF]

arXiv
A crucial component in many deep learning applications, such as Frequently Asked Questions (FAQ) and Retrieval-Augmented Generation (RAG), is dense retrieval. In this process, embedding models transform raw text into numerical vectors. However, the embedding models that currently excel on text embedding benchmarks, like the Massive Text Embedding ...
arxiv  

Deciphering the Interplay Between G‐Quadruplexes and Natural/Synthetic Polyamines

ChemBioChem, Volume 26, Issue 7, April 1, 2025.
The interplay between polyamines and G‐quadruplexes has been largely overlooked in the literature, even though PAs are ubiquitous metabolites in living cells and G4s are transient regulatory elements. Herein, we compile the investigations connecting G4s and biogenic polyamines or synthetic G4 ligands containing polyamines.
Ariadna Gil‐Martínez, Cristina Galiana‐Roselló, Andrea Lázaro‐Gómez, Laura Mulet‐Rivero, Jorge González‐García   +4 more
wiley   +1 more source

Evaluation of the Ochratoxin A Reduction and Physicochemical Properties of Green Coffee Beans Following Atmospheric Nonthermal Plasma and Plasma‐Activated Water Treatments

eFood, Volume 6, Issue 2, April 2025.
This study demonstrated that a combined treatment using plasma‐activated water (PAW) and nonthermal plasma (NTP) achieved the highest ochratoxin A reduction in green coffee beans, with up to 51.80% removal, compared to individual treatments. Notably, this combined approach preserved bean quality, showing minimal impact on color, phenolic content, and ...
Ashrie Yacab, Chia‐Min Lin, Pei‐Shan Chih, Trias Mahmudiono, Chih‐Yao Hou, Hsiu‐Ling Chen   +5 more
wiley   +1 more source

Predictive modeling and risk assessment strategies for enhancing dairy product safety: A comprehensive review

Food Safety and Health, Volume 3, Issue 2, Page 172-187, April 2025.
This review addresses risk assessment and predictive modeling strategies for dairy product safety. Key steps include hazard identification, characterization, exposure assessment, and risk characterization, aiding risk managers in mitigating risks. Abstract The dairy industry is a crucial part of the food sector, encompassing a wide range of raw, pre ...
Prachi Pahariya, Awani Shrivastav, Tridib Kumar Goswami, Ruplal Choudhary   +3 more
wiley   +1 more source

Sensitive and Highly Selective Detection of Organophosphorus Pesticides Using Organic Field‐Effect Transistors

SmartMat, Volume 6, Issue 2, April 2025.
The multichannel acetylcholinesterase‐OFET (AChE‐OFET) detection platform achieves ultrasensitive and simultaneous analysis of organophosphorus pesticides. Additionally, the portable monitoring applet is developed, enabling real‐time assessment of pesticide contamination status of samples based on current values. This work demonstrates that OFETs could
Yanan Lei, Haikuo Gao, Zhengsheng Qin, Jie Cheng, Can Gao, Dan Liu, Zhagen Miao, Xiangyu Tan, Pengsong Wang, Qingbin Li, Yu Zhang, Pu Wang, Xiaodan Ding, Ziyi Xie, Zhenling Liu, Jiaxin Yang, Yongshuai Wang, Yihan Zhang, Huanli Dong, Peilong Wang   +19 more
wiley   +1 more source

Connection Learning Healthcare System Hub of the Early Psychosis Intervention Network: Program and Participant Characteristics

Early Intervention in Psychiatry, Volume 19, Issue 4, April 2025.
ABSTRACT Aim Connection Learning Healthcare System, one of the eight hubs of the National Institute of Mental Health funded Early Psychosis Intervention Network, supports uniform data collection, analysis, feedback and infrastructure development to promote a culture of continuous quality improvement across 25 Coordinated Specialty Care programs serving
Monica E. Calkins, Megan Jumper, Arielle Ered, Fanghong Dong, Deepak K. Sarpal, Krista K. Baker, Donna J. Bencivengo, Russell L. Margolis, Robert W. Buchanan, Yasmine Boumaiz, Elizabeth Burris, Philip D. Campbell, K. N. Roy Chengappa, Catherine Conroy, Akinyi Cooke, Faith Dickerson, Nyasia Flowers, Mandy Fauble, Richard W. Goldberg, Alexander Harvin, Carolyn Howell, Christian Kelly, Julie Kreyenbuhl, Lan Li, Alicia Lucksted, Jill A. Marsteller, Alexander Moxam, Denise Namowicz, Swati Nayar, Jamie Oko, Jessie Riggs, Arunadevi Saravana, Rachel Scheinberg, William R. Smith, Richard States, Timur Suhail‐Sindhu, Jerome Taylor, Crystal L. Vatza, Max Wolcott, Christian G. Kohler, Melanie E. Bennett   +40 more
wiley   +1 more source

Systemic Lupus Erythematosus Exacerbates Hip Arthritis by Promoting Chondrocyte Pyroptosis in the Femoral Head via Activating the NF‐κB Pathway

Journal of Cellular and Molecular Medicine, Volume 29, Issue 7, April 2025.
ABSTRACT Systemic lupus erythematosus (SLE) is an autoimmune disease characterised by chronic inflammation and immune dysregulation, significantly impacting multiple organ systems, including the joints. While SLE is known to contribute to musculoskeletal complications, its role in hip arthritis development and the underlying mechanisms remain poorly ...
Xuliang Fang, Helou Zhang, Huiqing Zhou, Shuchao Shen, Zhaobai Lao, Zhiguo Zhang, Yishan Bian, Chengcong Zhou, Hongting Jin, Peijian Tong, Yanqun Huang, Hong Zhou, Hanbing Zeng, Fangda Fu, Chengliang Wu, Wenbiao Zheng, Hongfeng Ruan   +16 more
wiley   +1 more source

Modification of the existing maximum residue levels and setting of import tolerances for trifloxystrobin in various crops. [PDF]

EFSA J
European Food Safety Authority (EFSA), Bellisai G, Bernasconi G, Carrasco Cabrera L, Castellan I, Del Aguila M, Ferreira L, Greco L, Jarrah S, Leuschner R, Mioč A, Nave S, Reich H, Ruocco S, Scarlato AP, Simonati A, Szot M, Theobald A, Timofieieva O, Tiramani M, Verani A, Zioga E.   +21 more
europepmc   +1 more source

Thermal History and Source Rock Maturity Modeling of the Akri‐Bijeel Area, NW Zagros Fold Belt, Kurdistan Region, Northern Iraq

Journal of Petroleum Geology, Volume 48, Issue 2, Page 134-155, April 2025.
ABSTRACT The Akri‐Bijeel area in the NW Zagros fold‐and‐thrust belt (Kurdistan region of northern Iraq) has been the focus of petroleum exploration, and its subsurface has been drilled extensively. This makes it possible to combine outcrop studies of this mountainous region with subsurface data. The region has five potential or regionally proven source
Ayad N. F. Edilbi, Stephen A. Bowden, Abdalla Y. Mohamed, David Muirhead   +3 more
wiley   +1 more source