Results 81 to 90 of about 11,432,365 (216)

CD14 Plays a Critical Role in Pain and Inflammation Across Multiple Models of Post‐traumatic Osteoarthritis

open access: yesArthritis &Rheumatology, EarlyView.
Objective We employed global genetic deletion of CD14 and intra‐articular CD14 blockade across multiple murine osteoarthritis (OA) models that vary in severity of pathology and rate of progression to test the hypothesis that CD14 inhibition attenuates synovial inflammation and associated pain during disease progression.
Kevin G. Burt   +18 more
wiley   +1 more source

Evaluation of confirmatory data following the Article 12 MRL review for sodium 5‐nitroguaiacolate, sodium o‐nitrophenolate and sodium p‐nitrophenolate (sodium nitrocompounds)

open access: yesEFSA Journal, 2020
The applicant Asahi Chemical Europe s.r.o. submitted a request to the competent national authority in the Netherlands to evaluate the confirmatory data that were identified for the pesticide active substances sodium 5‐nitroguaiacolate, sodium o ...
European Food Safety Authority (EFSA)   +20 more
doaj   +1 more source

Kidney Hematopoietic Stem and Progenitor Cells Contribute to Myeloid Development and Pathology in Lupus Nephritis

open access: yesArthritis &Rheumatology, EarlyView.
Objective The hematopoietic system maintains homeostasis by balancing myeloid and lymphoid cell production in the bone marrow (BM). In response to increased hematopoietic demand, extramedullary hematopoiesis (EMH) may occur in nonlymphoid organs. We investigated the role of EMH and kidney‐resident hematopoietic stem and progenitor cells (HSPCs) in ...
Hansol Yi   +9 more
wiley   +1 more source

Multimodal representation learning for medical analytics - a systematic literature review

open access: yesHealth Informatics Journal
Objectives: Machine learning-based analytics over uni-modal medical data has shown considerable promise and is now routinely deployed in diagnostic procedures. However, patient data consists of diverse types of data.
Emil Riis Hansen, Tomer Sagi, Katja Hose
doaj   +1 more source

IgG Glycosylation‐Dependent CLEC7A Signaling Drives Podocyte Dysfunction in Lupus Nephritis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Lupus nephritis (LN) is a severe complication of systemic lupus erythematosus (SLE) that can lead to end‐stage kidney disease and increased mortality. IgG from patients with LN displays abnormal glycosylation, contributing to podocyte injury.
Rohit Upadhyay   +3 more
wiley   +1 more source

Purification of Disassembled Capsid Protein by Hydroxyapatite Chromatography Enhances Virus‐Like Particle Recovery

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Virus‐like particles (VLPs) are a promising modality with extensive applications in prophylactic and therapeutic vaccine design. Human Papillomavirus (HPV) vaccines are one such example where VLP vaccine applications have led to the successful reduction in HPV‐associated diseases, such as cervical cancer.
Nicholas Samuelson   +5 more
wiley   +1 more source

In‐line Raman spectroscopy real‐time glucose prediction method for commercial pneumococcal vaccine drug substance fermentation manufacturing process control

open access: yesBiotechnology Progress, EarlyView.
Abstract Traditional off‐line analysis methods to quantify residual metabolite concentrations in a drug substance fermentation process consume valuable time, require costly resources, and demand potentially hazardous manual operations when working with pathogenic biological organisms.
Griffin P. Thomas   +7 more
wiley   +1 more source

EFSA’s contribution to the implementation of the EU legislation on pesticide residues in food [PDF]

open access: yesEFSA Journal, 2012
<p>The active involvement of EFSA in the area of pesticide residues assessment started in 2006 following the adoption of new legislation on maximum residue levels (MRLs) of pesticides in food (Regulation (EC) No 396/2005).
Reich H   +4 more
doaj   +1 more source

Graphene Materials for Sustainable Energy Applications: A Contemporary Perspective

open access: yesCarbon Energy, EarlyView.
ABSTRACT Graphene has garnered significant attention as a promising material with great potential for contributing to sustainable energy initiatives, such as RE100 (100% renewable energy initiative) and CF100 (100% carbon‐free initiative). This review aims to explore the potential of graphene for advancing renewable energy applications by highlighting
Niraj Kumar   +3 more
wiley   +1 more source

Prioritised review of the existing maximum residue levels for dimethoate and omethoate according to Article 43 of Regulation (EC) No 396/2005

open access: yesEFSA Journal, 2016
In compliance with Article 43 of Regulation (EC) No 396/2005, EFSA received from the European Commission a mandate to conduct a prioritised review of the existing maximum residue levels (MRL) for dimethoate and omethoate, as a follow up of its ‘statement
European Food Safety Authority (EFSA)
doaj   +1 more source

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