Results 51 to 60 of about 424,109 (164)

Interim analysis of a phase 1 randomized clinical trial on the safety and immunogenicity of the mRNA-1283 SARS-CoV-2 vaccine in adults

Human Vaccines & Immunotherapeutics, 2023
This interim analysis of an ongoing phase 1 randomized clinical trial evaluated the safety, reactogenicity, and immunogenicity of mRNA-1283, a next-generation SARS-CoV-2 messenger RNA (mRNA)-based vaccine encoding two segments of the spike protein (i.e ...
Patrick Yassini, Mark Hutchens, Yamuna D. Paila, Lorraine Schoch, Anne Aunins, Uma Siangphoe, Robert Paris   +6 more
doaj   +1 more source

Effectiveness of the mRNA-1273 Vaccine during a SARS-CoV-2 Delta Outbreak in a Prison [PDF]

, 2021
Effectiveness of the mRNA-1273 Vaccine during a SARS-CoV-2 Delta Outbreak in a ...
Dorothy Leidner (13067292), David M Studdert (15655535), Yifan Zhang (119570), Jason R Andrews (14320521), Ying Li (38224), Lea Prince (178357), Elizabeth T Chin (15655532), Jeremy D Goldhaber-Fiebert (15655538), Joshua A Salomon (8674386), Elizabeth Long (3342410)   +9 more
core   +2 more sources

Adverse events reported after administration of BNT162b2 and mRNA-1273 COVID-19 vaccines among hospital workers: a cross-sectional survey-based study in a Spanish hospital [PDF]

, 2022
The World Health Organization declared COVID-19 a pandemic in March 2020. The first vaccine became available in December, with practically no post-marketing data. An analytical cross-sectional survey-based study was conducted in a third-level hospital in
Miguel Ángel (MA) Calleja-Hernández (11910136), Marta (M) Valera-Rubio (11910118), María Isabel (MI) Sierra-Torres (11910121), Jaime (J) Cordero-Ramos (11910127), María Reyes (MR) López-Márquez (11910130), Óscar (O) Cruz-Salgado (11910133), Raquel (R) Castillejo García (11910124)   +6 more
core   +3 more sources

Immunogenicity, reactogenicity, and safety of a second booster with BNT162b2 or full-dose mRNA-1273: A randomized VACCELERATE trial in adults aged ≥75 years (EU-COVAT-1-AGED Part B)

International Journal of Infectious Diseases
Objectives: To assess the safety and immunogenicity of a fourth vaccination (second booster) in individuals aged ≥75 years. Methods: Participants were randomized to BNT162b2 (Comirnaty, 30 µg) or messenger RNA (mRNA)-1273 (Spikevax, 100 µg).
Jannik Stemler, Lusine Yeghiazaryan, Christoph Stephan, Kristin Greve-Isdahl Mohn, Antonio-José Carcas-Sansuan, Esperanza Romero Rodriguez, José Moltó, Itziar Vergara Mitxeltorena, Tobias Welte, Birutė Zablockienė, Murat Akova, Ullrich Bethe, Sarah Heringer, Jon Salmanton-García, Julia Jeck, Lea Tischmann, Marouan Zarrouk, Arnd Cüppers, Lena M. Biehl, Jan Grothe, Sibylle C. Mellinghoff, Julia A. Nacov, Julia M. Neuhann, Rosanne Sprute, Jesús Frías-Iniesta, Riya Negi, Colette Gaillard, Gurvin Saini, Alejandro García León, Patrick W.G. Mallon, Christine Lammens, An Hotterbeekx, Katherine Loens, Surbhi Malhotra-Kumar, Herman Goossens, Samir Kumar-Singh, Franz König, Martin Posch, Philipp Koehler, Oliver A. Cornely   +39 more
doaj   +1 more source

Comparative effectiveness of BNT162b2 versus mRNA-1273 covid-19 vaccine boosting in England: matched cohort study in OpenSAFELY-TPP. [PDF]

, 2023
OBJECTIVE: To compare the effectiveness of the BNT162b2 mRNA (Pfizer-BioNTech) and mRNA-1273 (Moderna) covid-19 vaccines during the booster programme in England. DESIGN: Matched cohort study, emulating a comparative effectiveness trial.
Parker, Edward PK, Curtis, Helen J, Keogh, Ruth H, Bacon, Sebastian CJ, Palmer, Tom M, Mehrkar, Amir, Sterne, Jonathan A C, Alex J Walker, Williamson, Elizabeth J., Williamson, Elizabeth J, Miguel A Hernán, Brian MacKenna, Ben Goldacre, Elizabeth J Williamson, Jonathan A C Sterne, Horne, Elsie M F, Colm D Andrews, Walker, Venexia M, Jessica Morley, Sebastian C J Bacon, Horne, Elsie MF, MacKenna, Brian, Goldacre, Ben, Hernán, Miguel A, Sterne, Jonathan AC, William J Hulme, Ruth H Keogh, Walker, Venexia, Helen J Curtis, Andrews, Colm D, Edward P K Parker, Amir Mehrkar, Mehrkar-Asl, Amir, Morley, Jessica, Elsie M F Horne, Venexia Walker, Tom M Palmer, Hulme, William J, Walker, Alex J, Goldacre , Ben   +39 more
core   +1 more source

mRNA or ChAd0x1 COVID-19 vaccination of adolescents induces robust antibody and cellular responses with continued recognition of omicron following mRNA-1273 [PDF]

, 2022
Children and adolescents generally experience mild COVID-19. However, those with underlying physical health conditions are at a significantly increased risk of severe disease.
E Linley (21491957), S Ahmad (5575955), M Lim (9947426), M Ayodele (21491936), J Gunn (7338521), A Collins (7952654), J Poh (13650478), S Scott (7202651), F Baawuah (21491948), F Davis (13471717), ME Ramsay (21491906), M White (9887555), C Davis (7706315), J Zuo (9851051), G Ireland (13670413), I Okike (21491945), AJ Brent (7657916), J Wright (7728401), J Cohen (7751054), N Logan (14557460), R Azad (19229983), P Moss (7787393), E Jinks (21491939), B Brent (21491954), SN Ladhani (21491891), E Spalkova (14579618), D Waiblinger (21491960), J Beckmann (13279284), P Sylla (14579612), SM Nicol (21491942), AA Powell (21491933), G Amirthalingam (16342536), BJ Willett (14557457), K Brown (7679720), AC Dowell (21491930), R Bruton (14579627), J Garstang (21491951), J Kenny (13514788)   +37 more
core  

Delayed skin reaction after mRNA-1273 vaccine against SARS-CoV-2: a rare clinical reaction [PDF]

, 2021
BACKGROUND: The coronavirus disease 2019 (COVID-19) is associated with a wide clinical spectrum of skin manifestations, including urticarial, vesicular, vasculitic and chilblain-like lesions.
Rezazadeh, Amir, Albrecht G. Schmidt, Tom Luedde, Julia Reifenberger, Bölke, Edwin, Freise, Noemi F, Buhren, Bettina Alexandra, Stefan Salzmann, Martijn van Griensven, Meller, Stephan, Schneider, Marion, Torsten Feldt, Tamaskovics, Balint, Alessia Pedoto, Knoefel, Wolfram Trudo, Hoff, Norman-Philipp, Maas, Kitti, Schmidt, Albrecht G, Jensen, Björn Erik Ole, Homey, Bernhard, Schmidt, Livia, Fischer, Johannes C, Peter Arne Gerber, Pedoto, Alessia, Braun, Stephan A, Reifenberger, Julia, Wolfram Trudo Knoefel, Feldt, Torsten, Salzmann, Stefan, Braun, Stephan A., Matuschek, Christiane, Edwin Bölke, Livia Schmidt, Balint Tamaskovics, Firouzi-Memarpuri, Parnian, Grebe, Olaf, Kitti Maas, Verena Keitel, Johannes C. Fischer, Schmidt, Albrecht G., Boelke, Edwin, Noemi F. Freise, Budach, Wilfried, Fischer, Johannes C., van Griensven, Martijn; id_orcid, Christiane Matuschek, Haussmann, Jan, Häussinger, Dieter, Norman-Philipp Hoff, Freise, Noemi F., Björn Erik Ole Jensen, Marion Schneider, Stephan Meller, van Griensven, Martijn, Dieter Häussinger, Gerber, Peter Arne, Olaf Grebe, Jan Haussmann, Keitel, Verena, Wilfried Budach, Stephan A. Braun, Luedde, Tom, Parnian Firouzi-Memarpuri, Bernhard Homey, Amir Rezazadeh, Bettina Alexandra Buhren   +65 more
core   +1 more source

COVID arm as a common cutaneous manifestation after mRNA-1273 vaccination: a systematic review

BMC Infectious Diseases, 2023
Background By August 2022, CoronaVirus Disease-2019 (COVID-19) had caused 600 million illnesses and 6.5 million fatalities globally. A massive vaccination program is being implemented worldwide to suppress this condition.
Maulidina Agustin, Monica Trifitriana, Retno Danarti   +2 more
doaj   +1 more source

Effects of testosterone and high‐dose anabolic steroids on orthodontic‐induced bone remodeling and root resorption: An animal study

Journal of Periodontology, EarlyView.
Abstract Background This study investigates the impact of disruptions in testosterone levels on bone remodeling, root resorption, and periodontal ligament (PDL) during orthodontic tooth movement (OTM) in a pubertal male rat model. Methods Testosterone deficiency was induced through orchiectomy, and the anabolic‐androgenic steroid (AAS, testosterone ...
Caio Luiz Bitencourt Reis, Kelly Galisteu‐Luiz, Gabriela Leite Pedroso, Gustavo Lopes Puls, Leticia Cassaro, Bruno Boaventura Vieira, Fábio Lourenço Romano, Erika Calvano Küchler, Christian Kirschneck, Daniela Silva Barroso de Oliveira, Maria Bernadete Sasso Stuani, Mirian Aiko Nakane Matsumoto   +11 more
wiley   +1 more source

Neutralizing antibodies against SARS-CoV-2 of vaccinated healthcare workers in Taiwan

Annals of Medicine
Background Vaccination is one of the best ways to control the SARS-CoV-2 outbreak. In Taiwan, healthcare workers were prioritized for vaccination, but the effectiveness of these vaccines for them remains unclear.
Seto Priyambodo, Kuang-Che Kuo, Ken-Pen Weng, Shih-Feng Liu, Guan-Da Syu, Ho-Chang Kuo   +5 more
doaj   +1 more source