Results 61 to 70 of about 424,058 (165)

Impact of COVID‐19 and Vaccination on Lower Urinary Tract Symptoms: Insights From a Prospective Cohort Study

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims To evaluate the prevalence, clinical course, and risk factors of lower urinary tract symptoms (LUTS) in patients hospitalized with COVID‐19, and to assess associations with comorbidities, disease severity, and vaccination status. Methods We conducted a prospective cohort study of adult patients hospitalized with confirmed COVID‐19, who ...
Julia Duarte de Souza, Jose de Bessa Jr., Natássia Cristina Carboni Truzzi, Carolina Trigo Rocha, Bruno Camargo Rocha Paim de Araujo, Julyana Kanate Mazzoni Moromizato, Thulio Bosi Vieira Brandão, Rachel Mazoni Costa, Marcelo Hisano, Zein Mohamed Sammour, Homero Bruschini, William Carlos Nahas, Cristiano Mendes Gomes   +12 more
wiley   +1 more source

Vaccinations During Pregnancy Protect the Mother–Infant Dyad and Are Generally Safe

Acta Paediatrica, EarlyView.
ABSTRACT Aim Vaccination in pregnancy has a critical impact on mothers, foetuses and infants. The aim of this paper was to summarise key points presented by experts attending the 12th Maria Delivoria‐Papadopoulos Perinatal Symposium in March 2025 and further expand and update them.
Ariadne Malamitsi‐Puchner, Despina D. Briana, Gian Carlo Di Renzo   +2 more
wiley   +1 more source

Immunogenicity and safety of heterologous versus homologous prime-boost schedules with an adenoviral vectored and mRNA COVID-19 vaccine: a systematic review

Infectious Diseases of Poverty, 2022
Background Heterologous prime-boost with ChAdOx1 nCoV-19 vector vaccine (ChAd) and a messenger RNA vaccine (BNT or mRNA-1273) has been widely facilitating mass coronavirus disease 2019 (COVID-19) immunisation.
Jingjing Lv, Hui Wu, Junjie Xu, Jiaye Liu   +3 more
doaj   +1 more source

Temporal Association Between COVID‐19 Vaccination and HBsAg Loss in Chronic Hepatitis B Infection: An Interrupted Time Series Analysis

Alimentary Pharmacology &Therapeutics, EarlyView.
In 59,946 chronic hepatitis B patients followed over 23 years, COVID‐19 vaccination rollout was temporally associated with a 56% increase in HBsAg loss rates (peak 1.27 per 100 person‐years in 2022), followed by gradual waning. Negative control outcomes showed no similar pattern, supporting biological specificity. ABSTRACT Background and Aims Hepatitis
Jonggi Choi, Allison Carroll, Vy H. Nguyen, Megan Michta, Xuan Q. Zhang, Young‐Suk Lim, Raymond T. Chung   +6 more
wiley   +1 more source

MiR‐375 in CAFs‐Derived EVs Promotes HCC Progression via Regulating RASA1 and May Potentially Serve as a Biomarker for HCC

Cancer Science, EarlyView.
CAFs could transfer EVs miR‐375 into endothelial cells with a low level of RASA1 and further promote EC angiogenesis. Plasma EVs miR‐375 have the potential values as a novel diagnostic and prognostic biomarker for HCC. ABSTRACT Cancer‐associated fibroblasts (CAFs) in the tumor microenvironment play an important role in cancer initiation and progression
Wei Qin, Li Wang, Beiyuan Hu, Cuicui Xiao, XiaoYing Wu, Huan Tian, Songlin Peng   +6 more
wiley   +1 more source

Evaluation of mRNA-1273 Vaccine in Children 6 Months to 5 Years of Age

, 2022
BACKGROUND: The safety, reactogenicity, immunogenicity, and efficacy of the mRNA-1273 coronavirus disease 2019 (Covid-19) vaccine in young children are unknown. METHODS: Part 1 of this ongoing phase 2-3 trial was open label for dose selection; part 2 was
Chronis, Carey, Ramirez Schrempp, Daniela, Creech, C. Buddy, Griffin, Carl, Smith, Christopher A., Girard, Bethany, Garner, Fredric, Ampajwala, Madhavi, Smith, Christopher A, Berman, Gary, Zervos, Marcus, Anderson, Evan J., Das, Rituparna, Slobod, Karen, Johnson, Kimball A., Tomassini, Joanne E, Johnson, Kimball A, Muller, William J, Aunins, Anne, Turner, Mark, Tomassini, Joanne E., Ali, Kashif, Gerber, Jeffrey, Fuchs, George, Kuter, Barbara, McPhee, Roderick, Bennett, Richard L., Zervos, Marcus J, Nayak, Jennifer, Miller, Jacqueline M., Piramzadian, Arin, Berthaud, Vladimir, Muller, William J., Creech, C Buddy, Reuter, Caroline, Zhao, Xiaoping, Bennett, Richard L, Anderson, Evan J, Palanpurwala, Khozema, Hautzinger, Kelly, Deng, Weiping, Zhou, Honghong, KidCOVE Study Group, Rizzardi, Barbara, Pajon, Rolando, Hsia, Daniel, DeLucia, Dianne, Schnyder Ghamloush, Sabine, Miller, Jacqueline M   +48 more
core   +1 more source

Safety and durability of mRNA-1273–induced SARS-CoV-2 immune responses in adolescents: results from the phase 2/3 TeenCOVE trialResearch in context

EClinicalMedicine
Summary: Background: Longitudinal changes in vaccination-induced immune response remain inadequately characterized in adolescents. We present long-term safety, immunogenicity, and COVID-19 incidence following a 2-dose mRNA-1273 100-μg primary series ...
Amparo L. Figueroa, Kashif Ali, Gary Berman, Honghong Zhou, Weiping Deng, Wenqin Xu, Stephanie Lussier, Bethany Girard, Frank J. Dutko, Karen Slobod, Anne Yeakey, Frances Priddy, Jacqueline M. Miller, Rituparna Das   +13 more
doaj   +1 more source

IMUNOGENICIDADE DE UM PRIMEIRO REFORÇO COM BNT162B2 OU MRNA-1273 DE DOSE COMPLETA: UM ESTUDO RANDOMIZADO EM ADULTOS ≥75 ANOS (EU-COVAT-1) DO CONSÓRCIO VACCELERATE

Brazilian Journal of Infectious Diseases, 2023
Introdução: A vacinação continua sendo crucial para a proteção contra a infecção grave pelo SARS-CoV-2, especialmente na população idosa. Métodos: Avaliamos, em um estudo de fase II randomizado, controlado, adaptativo e multicêntrico, a segurança e a ...
Jon Salmanton-Garcia, Julia M. Neuhann, Jannik Stemler, Antonio Carcas, Samir Kumar-Singh, Alejandro García Leon, Franz König, Oliver A. Cornely   +7 more
doaj   +1 more source

Long‐read sequencing‐based atlas of tissue‐specific expression of DNM1L transcript variants

The FEBS Journal, EarlyView.
Targeted long‐read sequencing resolves full‐length DNM1L (Drp1) isoforms and reveals conserved, tissue‐specific expression patterns across human and mouse tissues. Functional assays show that Drp1 isoforms differ in their ability to drive mitochondrial fission, independent of abundance, with specific exons modulating activity.
Feng Yan, Jafar S. Jabbari, Naomi X. L. Ling, Anne M. Kong, Jia Q. Truong, Marnie L. Maddock, Ayeshah A. Rosdah, Christopher G. Langendorf, Lifang Zhang, Jarmon G. Lees, Sebastian Bass‐Stringer, Danise Ann Onda, Alice Pébay, Mirella Dottori, Kim Loh, Jessica K. Holien, Sean Lal, Nadia M. Davidson, Jonathan S. Oakhill, Shiang Y. Lim   +19 more
wiley   +1 more source

Antibody Response Induced by BNT162b2 and mRNA-1273 Vaccines against the SARS-CoV-2 in a Cohort of Healthcare Workers [PDF]

, 2022
The aim of this study was to characterize the antibody response induced by SARS-CoV-2 mRNA vaccines in a cohort of healthcare workers. A total of 2247 serum samples were analyzed using the Elecsys(®) Anti-SARS-CoV-2 S-test (Roche Diagnostics ...
Rodríguez, Sara, Sara Rodríguez, Serrano, Rosa M., Germà Julià, Amengual Guedan, Maria Jose, Navarro Rubio, Gemma, Navarro, Marta, Joan Calvet, Delgado, Juan F., Pilar Peña, Rosa M. Serrano, Gema Navarro, Berenguer-Llergo, Antoni, María J. Amengual, Sánchez, Noemí, Peña, Pilar, Gratacós, Jordi, Eva Van Den Eynde, Julià, Germà, Juan F. Delgado, Delgado, Juan Francisco, Espasa, Mateu, Antoni Berenguer-Llergo, Mateu Espasa, Calvet, Joan, Navarro, Gema, Amengual, María J., Jordi Gratacós, Van Den Eynde, Eva, Noemí Sánchez, Marta Navarro   +30 more
core   +1 more source