Results 61 to 70 of about 519,893 (158)

IgG anti-RBD levels during 8-month follow-up post-vaccination with BNT162b2 and mRNA-1273 vaccines in healthcare workers: A one-center study

Frontiers in Cellular and Infection Microbiology, 2022
IntroductionSince the COVID-19 outbreak, specific mRNA-based anti-SARS-CoV-2 vaccines have been developed and distributed worldwide. Because this is the first time that mRNA vaccines have been used, there are several questions regarding their capacity to
Sergio Gil-Manso, Roberto Alonso, Roberto Alonso, Roberto Alonso, Roberto Alonso, Pilar Catalán, Pilar Catalán, Pilar Catalán, Ignacio Sánchez-Arcilla, Marco Marzola, Rafael Correa-Rocha, Marjorie Pion, Patricia Muñoz, Patricia Muñoz, Patricia Muñoz, Patricia Muñoz, Gregorio Marañón Microbiology-ID COVID-19 Study Group, Luis Alcalá, Teresa Aldámiz, Roberto Alonso, Beatriz Álvarez, Ana Álvarez-Uría, Alexi Arias, Elena Bermúdez, Emilio Bouza, Sergio Buenesta do-Serrano, Almudena Burillo, Raquel Carrillo, Pilar Catalán, Emilia Cercenado, Alejandro Cobos, Cristina Díez, Pilar Escribano, Agustín Estévez, Chiara Fanciulli, Alicia Galar, Mª Dolores García, Darío García de Viedma, Paloma Gijón, Adolfo González, Helmuth Guillén, Jesús Guinea, Marta Herranz, Álvaro Irigoyen, Laura Vanessa Haces, Martha Kestler, Juan Carlos López, Carmen Narcisa Losada, Marina Machado, Mercedes Marín, Pablo Martín-Rabadán, Andrea Molero-Salinas, Pedro Montilla, Patricia Muñoz, María Olmedo, Belén Padilla, Rosalía Palomino-Cabrera, María Palomo, María Jesús Pérez-Granda, Daniel Peñas-Utrilla, Laura Pérez-Lago, Leire Pérez, Elena Reigadas, Cristina Rincón, Belén Rodríguez, Sara Rodríguez, Cristina Rodríguez-Grande, Adriana Rojas, María Jesús Ruiz-Serrano, Carlos Sánchez, Mar Sánchez, Amadeo Sanz-Pérez, Julia Serrano, Francisco Tejerina, Maricela Valerio, Mª Cristina Veintimilla, Lara Vesperinas, Teresa Vicente, Sofíade la Villa   +76 more
doaj   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Assessment of the Neutralizing Antibody Response of BNT162b2 and mRNA-1273 SARS-CoV-2 Vaccines in Naïve and Previously Infected Individuals: A Comparative Study

Vaccines, 2022
The currently authorized mRNA COVID-19 vaccines, Pfizer-BNT162b2 and Moderna-mRNA-1273, offer great promise for reducing the spread of the COVID-19 by generating protective immunity against SARS-CoV-2.
Farah M. Shurrab, Duaa W. Al-Sadeq, Haissam Abou-Saleh, Nader Al-Dewik, Amira E. Elsharafi, Fatima M. Hamaydeh, Bushra Y. Abo Halawa, Tala M. Jamaleddin, Huda M. Abdul Hameed, Parveen B. Nizamuddin, Fathima Humaira Amanullah, Hanin I. Daas, Laith J. Abu-Raddad, Gheyath K. Nasrallah   +13 more
doaj   +1 more source

Impact of COVID‐19 and Vaccination on Lower Urinary Tract Symptoms: Insights From a Prospective Cohort Study

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims To evaluate the prevalence, clinical course, and risk factors of lower urinary tract symptoms (LUTS) in patients hospitalized with COVID‐19, and to assess associations with comorbidities, disease severity, and vaccination status. Methods We conducted a prospective cohort study of adult patients hospitalized with confirmed COVID‐19, who ...
Julia Duarte de Souza, Jose de Bessa Jr., Natássia Cristina Carboni Truzzi, Carolina Trigo Rocha, Bruno Camargo Rocha Paim de Araujo, Julyana Kanate Mazzoni Moromizato, Thulio Bosi Vieira Brandão, Rachel Mazoni Costa, Marcelo Hisano, Zein Mohamed Sammour, Homero Bruschini, William Carlos Nahas, Cristiano Mendes Gomes   +12 more
wiley   +1 more source

Immunogenicity and safety of heterologous versus homologous prime-boost schedules with an adenoviral vectored and mRNA COVID-19 vaccine: a systematic review

Infectious Diseases of Poverty, 2022
Background Heterologous prime-boost with ChAdOx1 nCoV-19 vector vaccine (ChAd) and a messenger RNA vaccine (BNT or mRNA-1273) has been widely facilitating mass coronavirus disease 2019 (COVID-19) immunisation.
Jingjing Lv, Hui Wu, Junjie Xu, Jiaye Liu   +3 more
doaj   +1 more source

Chemical and Biological Determinants of PEG‐Lipid Shedding From Therapeutic Nanoparticles

Small, EarlyView.
PEG‐lipids play a central role in governing lipid nanoparticle stability, targeting, and function. However, PEG‐lipids can “shed” from the nanoparticle surface in biological environments, with the extent and kinetics of shedding influenced by chemical and biological factors.
Ethan P. Cisneros, Aadya S. Wijesekera, Lisa R. Volpatti   +2 more
wiley   +1 more source

Safety and durability of mRNA-1273–induced SARS-CoV-2 immune responses in adolescents: results from the phase 2/3 TeenCOVE trialResearch in context

EClinicalMedicine
Summary: Background: Longitudinal changes in vaccination-induced immune response remain inadequately characterized in adolescents. We present long-term safety, immunogenicity, and COVID-19 incidence following a 2-dose mRNA-1273 100-μg primary series ...
Amparo L. Figueroa, Kashif Ali, Gary Berman, Honghong Zhou, Weiping Deng, Wenqin Xu, Stephanie Lussier, Bethany Girard, Frank J. Dutko, Karen Slobod, Anne Yeakey, Frances Priddy, Jacqueline M. Miller, Rituparna Das   +13 more
doaj   +1 more source

Vaccinations During Pregnancy Protect the Mother–Infant Dyad and Are Generally Safe

Acta Paediatrica, EarlyView.
ABSTRACT Aim Vaccination in pregnancy has a critical impact on mothers, foetuses and infants. The aim of this paper was to summarise key points presented by experts attending the 12th Maria Delivoria‐Papadopoulos Perinatal Symposium in March 2025 and further expand and update them.
Ariadne Malamitsi‐Puchner, Despina D. Briana, Gian Carlo Di Renzo   +2 more
wiley   +1 more source

Comparative effectiveness of BNT162b2 versus mRNA-1273 covid-19 vaccine boosting in England: matched cohort study in OpenSAFELY-TPP. [PDF]

, 2023
OBJECTIVE: To compare the effectiveness of the BNT162b2 mRNA (Pfizer-BioNTech) and mRNA-1273 (Moderna) covid-19 vaccines during the booster programme in England. DESIGN: Matched cohort study, emulating a comparative effectiveness trial.
Parker, Edward PK, Curtis, Helen J, Keogh, Ruth H, Bacon, Sebastian CJ, Palmer, Tom M, Mehrkar, Amir, Sterne, Jonathan A C, Alex J Walker, Williamson, Elizabeth J., Williamson, Elizabeth J, Miguel A Hernán, Brian MacKenna, Ben Goldacre, Elizabeth J Williamson, Jonathan A C Sterne, Horne, Elsie M F, Colm D Andrews, Walker, Venexia M, Jessica Morley, Sebastian C J Bacon, Horne, Elsie MF, MacKenna, Brian, Goldacre, Ben, Hernán, Miguel A, Sterne, Jonathan AC, William J Hulme, Ruth H Keogh, Walker, Venexia, Helen J Curtis, Andrews, Colm D, Edward P K Parker, Amir Mehrkar, Mehrkar-Asl, Amir, Morley, Jessica, Elsie M F Horne, Venexia Walker, Tom M Palmer, Hulme, William J, Walker, Alex J, Goldacre , Ben   +39 more
core   +1 more source

IMUNOGENICIDADE DE UM PRIMEIRO REFORÇO COM BNT162B2 OU MRNA-1273 DE DOSE COMPLETA: UM ESTUDO RANDOMIZADO EM ADULTOS ≥75 ANOS (EU-COVAT-1) DO CONSÓRCIO VACCELERATE

Brazilian Journal of Infectious Diseases, 2023
Introdução: A vacinação continua sendo crucial para a proteção contra a infecção grave pelo SARS-CoV-2, especialmente na população idosa. Métodos: Avaliamos, em um estudo de fase II randomizado, controlado, adaptativo e multicêntrico, a segurança e a ...
Jon Salmanton-Garcia, Julia M. Neuhann, Jannik Stemler, Antonio Carcas, Samir Kumar-Singh, Alejandro García Leon, Franz König, Oliver A. Cornely   +7 more
doaj   +1 more source