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SARS-CoV-2 Receptor Binding Domain (RBD) Protein-Protein Conjugate Induces Similar or Better Antibody Responses as Spike mRNA in Rhesus Macaques. [PDF]

open access: yesVaccines (Basel)
Scaria PV   +19 more
europepmc   +1 more source

Passive shaping of intra- and intercellular m6A dynamics via mRNA metabolism. [PDF]

open access: yesElife
Dierks D   +13 more
europepmc   +1 more source
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RIBONUCLEOPROTEIN PARTICLES CONTAINING mRNA and pre-mRNA

Acta Endocrinologica, 1973
ABSTRACT This paper is a review of the data concerning the nature, structural organization, properties and biological significance of the particles, containing mRNA and pre-mRNA (precursor of mRNA), i. e., (1) nuclear pre-mRNA-containing particles (2) free cytoplasmic mRNP (ribonucleoproteins), or informosomes (3) polysome-bound mRNP.
G. P. Georgiev   +2 more
openaire   +3 more sources

mRNA turnover

Current Opinion in Cell Biology, 2001
Nuclear RNA-binding proteins can record pre-mRNA processing events in the structure of messenger ribonucleoprotein particles (mRNPs). During initial rounds of translation, the mature mRNP structure is established and is monitored by mRNA surveillance systems. Competition for the cap structure links translation and subsequent mRNA degradation, which may
P, Mitchell, D, Tollervey
openaire   +2 more sources

Pre-mRNA processing and mRNA nuclear export

Current Opinion in Cell Biology, 1989
The primary transcript of a prokaryotic gene is translated immediately following or during synthesis, whereas in eukaryotes, messenger RNA (mRNA) precursors (premRNAs) are synthesized in the nucleus and are then structurally altered and relocated to the cytoplasm before translation (Fig. 1).
openaire   +3 more sources

Hybridization of mRNA and pre-mRNA with the sequences forming double-stranded structures in pre-mRNA

Molecular Biology Reports, 1973
About 25% of the double-stranded sequences isolated from pre-mRNA are able to hybridize, after melting, with either mRNA or non-melted pre-mRNA. The retention of one branch of pre-mRNA hairpin in mRNA was suggested. It was also found that in addition to the hairpin-like structures comprising about 3% of the total sequences another 15% of the pre-mRNA ...
Georgii P. Georgiev   +2 more
openaire   +3 more sources

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