Results 371 to 380 of about 3,391,200 (390)
Some of the next articles are maybe not open access.
2014
Uridine addition at the 3' end of RNAs (i.e., uridylation) emerges as a critical posttranscriptional modification promoting RNA degradation. Uridylation has been notably linked to the degradation of small RNAs, correlated with the 5' shortening of RISC-cleaved transcripts and the degradation of mRNAs.
François M. Sement, Dominique Gagliardi
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Uridine addition at the 3' end of RNAs (i.e., uridylation) emerges as a critical posttranscriptional modification promoting RNA degradation. Uridylation has been notably linked to the degradation of small RNAs, correlated with the 5' shortening of RISC-cleaved transcripts and the degradation of mRNAs.
François M. Sement, Dominique Gagliardi
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mRNA-based cancer therapeutics
Nature Reviews. Cancer, 2023Chuang Liu+5 more
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CYP3A5 mRNA Degradation by Nonsense-Mediated mRNA Decay
Molecular Pharmacology, 2005The total CYP3A5 mRNA level is significantly greater in carriers of the CYP3A5*1 allele than in CYP3A5*3 homozygotes. Most of the CYP3A5*3 mRNA includes an intronic sequence (exon 3B) containing premature termination codons (PTCs) between exons 3 and 4.
Florent Busi, Thierry Cresteil
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The cytoskeleton and mRNA localization
Current Opinion in Cell Biology, 1992The localization of mRNA appears to facilitate protein sorting, so that proteins are synthesized in specific cellular regions. The spatial information on the mRNA may be transduced by proteins that recognize specific localizing sequences on the 3' end and then chaperone the mRNA, presumably along filaments, to its destination. Additional sequences such
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Molecular Microbiology, 2006
SummaryAlthough plasmid‐borne and chromosomal toxin–antitoxin (TA) operons have been known for some time, the recent identification of mRNA as the target of at least two different classes of toxins has led to a dramatic renewal of interest in these systems as mediators of stress responses.
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SummaryAlthough plasmid‐borne and chromosomal toxin–antitoxin (TA) operons have been known for some time, the recent identification of mRNA as the target of at least two different classes of toxins has led to a dramatic renewal of interest in these systems as mediators of stress responses.
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Reading, writing and erasing mRNA methylation
Nature reviews. Molecular cell biology, 2019S. Zaccara, R. Ries, S. Jaffrey
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Initiation Factor/mRNA Interactions and mRNA Recognition
1982The recognition of mRNA and its binding to ribosomes are generally considered to be of key importance to translational control. That is, the decision whether a given mRNA species will be translated during cell growth, differentiation or virus infection is largely determined at initiation.
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