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Identification of potential biomarkers for SLE through mRNA expression profiling
Journal of Immunoassay and Immunochemistry, 2023Systemic lupus erythematosus (SLE) is an autoimmune disease that influences numerous body systems. Furin, tristetraprolin (TTP), and NOD, LRR, and pyrin domain-containing protein 3 (NLRP3) contribute in developing autoimmune illnesses.Understandthe role of furin, TTP, and NLRP3 mRNA gene expression in SLE pathogenesis and prognosis.
Sara Kamal Rizk +4 more
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Differential expression profile analysis of PSTK‐regulated mRNAs in podocytes
Journal of Cellular Biochemistry, 2019AbstractThis study aimed to elucidate the precise mechanisms underlying the protective effects of phosphoseryl‐tRNA kinase (PSTK) against cisplatin‐induced podocyte injury. PSTK overexpression and knockdown vectors were generated and transfected into murine podocyte cells‐5.
Dong Zheng +6 more
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Comprehensive Analysis of lncRNA and mRNA Expression Profiles in Lung Cancer
Clinical Laboratory, 2017Lung cancer is one of the most common malignancies across the world. Long noncoding RNAs (lncRNAs) play an important role in the pathology. This study was to compare the lncRNA and mRNA of lung cancer. The aim of this study was to compare the lncRNA and mRNA expression profiles, their related biological functions, and pathways in lung cancer.Human lung
Ran, Chen +8 more
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Profile of cytokine mRNA expression in peri-implantation human endometrium
Molecular Human Reproduction, 1998The human embryo and subsequent fetus is a semi-allograft and immunologically foreign to the mother. Successful embryonic implantation and maintenance of normal pregnancy depends on intricate interactions between the invading embryo, maternal endometrium and maternal immune response.
K J, Lim +5 more
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Northern Blot Analysis for Expression Profiling of mRNAs and Small RNAs
2012Northern analysis is a conventional but gold standard method for detection and quantification of gene expression changes. It not only detects the presence of a transcript but also indicates size and relative comparison of transcript abundance on a single membrane.
Ankur R, Bhardwaj +3 more
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mRNA and microRNA Purity and Integrity: The Key to Success in Expression Profiling
2014RNA quality control is a crucial step in guaranteeing integer nondegraded RNA and receiving meaningful results in gene expression profiling experiments, using micro-array, RT-qPCR (Reverse-Transcription quantitative PCR), or Next-Generation-Sequencing by RNA-Seq or small-RNA Seq. Therefore, assessment of RNA integrity and purity is very essential prior
Benedikt, Kirchner +3 more
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miRNA and mRNA expression profiling reveals potential biomarkers for metastatic cutaneous melanoma
Expert Review of Anticancer Therapy, 2021Queqiao Bian
exaly