Results 181 to 190 of about 19,056,956 (378)

trans-acting regulation of bovine leukemia virus mRNA processing [PDF]

, 1988
David Derse
openalex   +1 more source

Lyophilization process optimization and molecular dynamics simulation of mRNA-LNPs for SARS-CoV-2 vaccine [PDF]

, 2023
Peng Yu, Mingyuan Li, Lin Jia, Yanbo Xie, Wenlin Ma, Zhihong Yan, Yuman Ma, Jie Deng, Ali Zhu, Xue Wei, Wen‐Yu Su, Xiaofeng Liu, Shiqin Li, Haomeng Wang, Tao Zhu   +14 more
openalex   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Pkhd1^cyli/cyli mice have altered renal Pkhd1 mRNA processing and hormonally sensitive liver disease. [PDF]

J Mol Med (Berl), 2023
Yang C, Harafuji N, Caldovic L, Yu W, Boddu R, Bhattacharya S, Barseghyan H, Gordish-Dressman H, Foreman O, Bebok Z, Eicher EM, Guay-Woodford LM.   +11 more
europepmc   +1 more source

HERVs, transposons and human diseases : part 3 [PDF]

, 2012
Part 1 and 2 of this article can be found through theses links: https://www.um.edu.mt/library/oar//handle/123456789/12961 https://www.um.edu.mt/library/oar//handle/123456789/13012Part 3 of the article.
Baldacchino, Sandra, Grech, Alfred
core   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

NONO enhances mRNA processing of super-enhancer-associated GATA2 and HAND2 genes in neuroblastoma. [PDF]

EMBO Rep, 2023
Zhang S, Cooper JA, Chong YS, Naveed A, Mayoh C, Jayatilleke N, Liu T, Amos S, Kobelke S, Marshall AC, Meers O, Choi YS, Bond CS, Fox AH.   +13 more
europepmc   +1 more source

Crystal Structure of the HEAT Domain from the Pre-mRNA Processing Factor Symplekin

, 2009
Sarah Kennedy, Monica L. Frazier, Mindy Steiniger, Ann M. Mast, William F. Marzluff, Matthew R. Redinbo   +5 more
openalex   +1 more source

CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing’s sarcoma

Nature Chemical Biology, 2019
Nathan T. Ross, F. Lohmann, Seth Carbonneau, A. Fazal, W. Weihofen, S. Gleim, M. Salcius, Frederic D. Sigoillot, Martin Hénault, S. Carl, Juan B. Rodríguez-Molina, H. Miller, S. Brittain, Jason Murphy, M. Zambrowski, Geoffrey Boynton, Yuan Wang, Aye T. Chen, Gregory J. Molind, Johannes H. Wilbertz, Caroline G. Artus-Revel, M. Jia, Favour A. Akinjiyan, Jonathan Turner, Judith Knehr, Walter Carbone, S. Schuierer, John Reece-Hoyes, Kevin Xie, Chitra Saran, Eric T. Williams, G. Roma, Matt Spencer, J. Jenkins, Elizabeth L. George, J. Thomas, G. Michaud, M. Schirle, John A. Tallarico, L. A. Passmore, J. Chao, Rohan E. J. Beckwith   +41 more
semanticscholar   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source