Results 191 to 200 of about 19,056,956 (378)

Nsp14 of SARS-CoV-2 inhibits mRNA processing and nuclear export by targeting the nuclear cap-binding complex. [PDF]

Nucleic Acids Res, 2023
Katahira J, Ohmae T, Yasugi M, Sasaki R, Itoh Y, Kohda T, Hieda M, Yokota Hirai M, Okamoto T, Miyamoto Y.   +9 more
europepmc   +1 more source

Alternative Splicing and Polyadenylation Contribute to the Generation of hERG1 C-terminal Isoforms

, 2010
The human ether-a-go-go-related gene 1 (hERG1) encodes the pore-forming subunit of the rapidly activating delayed rectifier potassium channel. Several hERG1 isoforms with different N- and C-terminal ends have been identified.
Gong, Qiuming, Stump, Matthew R., Dunn, A. Russell, Deng, Vivianne, Zhou, Zhengfeng   +4 more
core  

The Composition of the Arabidopsis RNA Polymerase II Transcript Elongation Complex Reveals the Interplay between Elongation and mRNA Processing Factors[OPEN]

The Plant Cell, 2017
Wojciech Antosz, Alexander Pfab, Hans F. Ehrnsberger, Philipp Holzinger, Karin Köllen, S. A. Mortensen, A. Bruckmann, Thomas Schubert, G. Längst, Joachim Griesenbeck, V. Schubert, Marion Grasser, K. Grasser   +12 more
semanticscholar   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Hepatitis, testicular degeneration, and ataxia in DIDO3-deficient mice with altered mRNA processing. [PDF]

Cell Biosci, 2022
Gutiérrez J, van Wely KHM, Martínez-A C.   +2 more
europepmc   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Correction to: Hepatitis, testicular degeneration, and ataxia in DIDO3-deficient mice with altered mRNA processing. [PDF]

Cell Biosci, 2022
Gutiérrez J, van Wely KHM, Martínez-A C.   +2 more
europepmc   +1 more source

Structure of the Yeast SR Protein Npl3 and Interaction with mRNA 3′-End Processing Signals

, 2007
Pritilekha Deka, Miriam E. Bucheli, Claire Moore, Stephen Buratowski, Gabriele Varani   +4 more
openalex   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Human histone pre-mRNA assembles histone or canonical mRNA-processing complexes by overlapping 3'-end sequence elements. [PDF]

Nucleic Acids Res, 2022
Ielasi FS, Ternifi S, Fontaine E, Iuso D, Couté Y, Palencia A.   +5 more
europepmc   +1 more source