Results 251 to 260 of about 18,476,439 (363)

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

MISF2 Encodes an Essential Mitochondrial Splicing Cofactor Required for nad2 mRNA Processing and Embryo Development in Arabidopsis thaliana. [PDF]

Int J Mol Sci, 2022
Nguyen TT, Best C, Shevtsov S, Zmudjak M, Quadrado M, Mizrahi R, Zer H, Mireau H, Ostersetzer-Biran O.   +8 more
europepmc   +1 more source

Roles for SUMO in pre‐mRNA processing

Wiley Interdisciplinary Reviews - RNA, 2016
Patrick K. Nuro-Gyina, J. Parvin
semanticscholar   +1 more source

LIN28B Promotes Cancer Cell Dissemination and Angiogenesis

Advanced Biology, EarlyView.
Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo, Sara Menegazzo, Marcella Pantile, Silvia Bresolin, Carlo Zanon, Alessandro Davini, Massimiliano Mazzone, Alessandra Biffi, Sanja Aveic   +8 more
wiley   +1 more source

Pre-mRNA processing factors are required for nuclear export [PDF]

, 2000
Alexander S. Brodsky, Pamela A. Silver
openalex   +1 more source

Inhibition of Glutamine Metabolism Attenuates Tumor Progression Through Remodeling of the Macrophage Immune Microenvironment

Advanced Biology, EarlyView.
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li, Sepehr Akhtarkhavari, Sumeng Qi, Jiawei Fan, Tu‐Yung Chang, Yao‐An Shen, JinMing Yang, Barbara S. Slusher, Ie‐Ming Shih, Stephanie Gaillard, Tian‐Li Wang   +10 more
wiley   +1 more source

Unconventional mRNA processing and degradation pathways for the polycistronic yrzI (spyTA) mRNA in Bacillus subtilis. [PDF]

FEBS Lett
Gilet L, Leroy M, Maes A, Condon C, Braun F.   +4 more
europepmc   +1 more source

Conserved long-range base pairings are associated with pre-mRNA processing of human genes. [PDF]

Nat Commun, 2021
Kalmykova S, Kalinina M, Denisov S, Mironov A, Skvortsov D, Guigó R, Pervouchine D.   +6 more
europepmc   +1 more source

A novel splice-acceptor site mutation (IVS13-2A>T) of polycystic kidney disease 1 (PKD1) gene resulting in an RNA processing defect with a 74-nucleotide deletion in exon 14 of the mRNA transcript [PDF]

, 2000
Anna Thongnoppakhun, Nanyawan Rungroj, Prapon Wilairat, Kriengsak Vareesangthip, C Sirinavin, Pa‐thai Yenchitsomanus   +5 more
openalex   +1 more source

Chromatin structure and pre-mRNA processing work together

Transcription, 2016
S. Jimeno-González, J. Reyes
semanticscholar   +1 more source